Last reviewed · How we verify
NCT04677907: TRECK
TRabecular Metal Economic and Clinical Knee Trial
NA trial testing Persona (Zimmer) posterior stabilised uncemented Trabecular Metal™ (Tibia and Femur) prosthesis in Total Knee Replacement in 144 participants. Currently enrolling.
30 November 2025
Quick facts
| Lead sponsor | NHS Greater Glasgow and Clyde |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 144 |
| Start date | 10 May 2022 |
| Primary completion | 30 November 2025 |
| Estimated completion | 30 June 2035 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Persona (Zimmer) posterior stabilised uncemented Trabecular Metal™ (Tibia and Femur) prosthesis
- Persona (Zimmer) posterior stabilised cemented Trabecular Metal™ (Tibia and Femur) prosthesis
Conditions studied
- Total Knee Replacement — all drugs for Total Knee Replacement →
- Orthopedics — all drugs for Orthopedics →
Sponsor
NHS Greater Glasgow and Clyde — full company profile →
Who can join
18 and older, any sex, with Total Knee Replacement or Orthopedics. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To compare the differences, if any, in clinical outcome, patient satisfaction and survivorship between cemented and uncemented Total Knee Replacements (TKR)? To investigate if there are health economic implications of using uncemented TKRs in the NHS?
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04677907
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Total Knee Replacement
Currently open trials in the same condition.
- NCT06929871 — Mako Cementless TKA vs Mako Cemented TKA · NA · recruiting
- NCT07120191 — An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool · recruiting
- NCT06578936 — The Effect of Abdominal Massage and Warm Application on Excretory Activity in Patients Undergoing Total Knee Replacement · NA · recruiting
- NCT07275983 — Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia · recruiting
- NCT06269770 — Tapentadol vs Tramadol in Total Knee Arthroplasty · Phase 4 · recruiting
Other NHS Greater Glasgow and Clyde trials
Trials by the same sponsor.
- NCT07403890 — Rewiring the Brain-Immune Axis for Chronic Pain Using Transcranial Magnetic Stimulation in Psoriatic Arthritis · NA · not yet recruiting
- NCT07372508 — Glasgow Low-dose CT and AI-based Diagnostics to Case Find Lung Cancer and Other Cardio-respiratory Long-term Conditions · NA · not yet recruiting
- NCT07391280 — Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department · NA · not yet recruiting
- NCT07048184 — Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing · Phase 2 · not yet recruiting
- NCT06786936 — Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04677907 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by NHS Greater Glasgow and Clyde
- Last refreshed: 25 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04677907.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing