NCT04674852 is a NA clinical trial of Research Marker in Breast Neoplasm Female, sponsored by Mayo Clinic.

Who is sponsoring NCT04674852?

NCT04674852 is sponsored by Mayo Clinic.

What drugs are being tested in NCT04674852?

Interventions in NCT04674852: Research Marker.

What condition does NCT04674852 study?

NCT04674852 studies Breast Neoplasm Female, Ultrasound Therapy; Complications.

Is NCT04674852 still recruiting?

NCT04674852 is currently completed. Last updated 20 January 2023.

Last reviewed 2023-01-20 · How we verify

NCT04674852

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Mayo Designed Soft Tissue Ultrasound-Detectable Marker

Completed NA Last updated 20 January 2023

What this trial tests

NA trial testing Research Marker in Breast Neoplasm Female in 8 participants. Completed in 7 April 2022.

Timeline

2 November 2020

Primary endpoint
26 July 2021

7 April 2022

Quick facts

Lead sponsor	Mayo Clinic
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	device feasibility
Enrollment	8
Start date	2 November 2020
Primary completion	26 July 2021
Estimated completion	7 April 2022
Sites	1 location across United States

Drugs / interventions tested

Research Marker

Conditions studied

Breast Neoplasm Female — all drugs for Breast Neoplasm Female →
Ultrasound Therapy; Complications — all drugs for Ultrasound Therapy; Complications →

Sponsor

Mayo Clinic

Who can join

18 and older, female only, with Breast Neoplasm Female or Ultrasound Therapy; Complications. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Researchers are trying to determine if the Mayo marker is easily seen with ultrasound making it easier, faster, and more accurate for preoperative localization of the biopsied positive lymph node.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Ultrasonographic Detection and Surgical Retrieval of a Nonmetallic Twinkle Marker in Breast Cancer: Pilot Study.
Jakub JW, Hesley GK, Larson NB, Yaszemski MJ, et al · · 2022 · cited 3× · PMID 36367449 · DOI 10.1148/rycan.220053

Verify or expand the search:

Other recruiting trials for Breast Neoplasm Female

Currently open trials in the same condition.

NCT07465523 — A Novel Approach in the Evaluation of Breast Masses With Doppler US · recruiting
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NCT04812652 — Digitally Distributed Yoga for Women Treated for Breast Cancer · NA · active not recruiting

Other Mayo Clinic trials

Trials by the same sponsor.

NCT07126548 — A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men · NA · not yet recruiting
NCT07221656 — Evaluation of Prolonged Asparaginase Activity Levels After Calaspargase Pegol Administration · not yet recruiting
NCT06891001 — The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, · NA · not yet recruiting
NCT07169799 — Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE) · NA · recruiting
NCT07086183 — Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04674852 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
Last refreshed: 20 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04674852.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing