Last reviewed · How we verify
NCT04668534
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Functional Dyspepsia
NA trial testing taVNS 10 in Functional Dyspepsia in 300 participants. Status unknown.
28 December 2021
Quick facts
| Lead sponsor | Air Force Military Medical University, China |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 300 |
| Start date | 1 November 2020 |
| Primary completion | 28 December 2021 |
| Estimated completion | 28 March 2022 |
| Sites | 3 locations across China |
Drugs / interventions tested
- taVNS 10
- taVNS 25
- Control
Conditions studied
- Functional Dyspepsia — all drugs for Functional Dyspepsia →
Sponsor
Air Force Military Medical University, China
Who can join
Adults 18 to 65, any sex, with Functional Dyspepsia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients with dyspeptic symptoms vary from 10% to 20% globally. Up to 70% of patients with dyspepsia who undergo endoscopy have unremarkable examination and are diagnosed with functional dyspepsia (FD). Given the lack of information related to its pathophysiology, the treatment is largely empirical and of limited efficacy. Previous small study showed therapeutic potential of transcutaneous auricular vagal nerve stimulation (taVNS) for FD. This study aims to investigate whether taVNS can improve the dyspeptic symptoms of patients with FD.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Transcutaneous Auricular Vagal Nerve Stimulation Is Effective for the Treatment of Functional Dyspepsia: A Multicenter, Randomized Controlled Study.
Shi X, Zhao L, Luo H, Deng H, et al · · 2024 · cited 25× · PMID 37787432 · DOI 10.14309/ajg.0000000000002548 -
331: CLINICAL CHARACTERISTICS AND LONG-TERM OUTCOMES IN PATIENTS WITH CYCLIC VOMITING SYNDROME: A 12-YEAR EXPERIENCE AT A TERTIARY REFERRAL CENTER
· 2022
Verify or expand the search:
- PubMed search for NCT04668534
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Functional Dyspepsia
Currently open trials in the same condition.
- NCT07442734 — Auricular Stimulation for Functional Dyspepsia With Insomnia: Efficacy and Mechanisms · NA · recruiting
- NCT07250308 — Correlation Study of Atrophic Gastritis and Dyspepsia Symptoms · recruiting
- NCT07187492 — Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia · Phase 4 · recruiting
- NCT07182890 — Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia · Phase 4 · recruiting
- NCT07210294 — Press Needle on Body Acupuncture Points and Auricular Acupuncture Points on Functional Dyspepsia · NA · recruiting
Other Air Force Military Medical University, China trials
Trials by the same sponsor.
- NCT07535138 — Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy · EARLY_PHASE1 · not yet recruiting
- NCT07454408 — Evaluation of the Outcome of Fecal Microbiota Transplantation · Phase 1, PHASE2 · not yet recruiting
- NCT07329660 — Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients · NA · not yet recruiting
- NCT07365345 — Frequency of Electrical Acupoint Stimulation on Hypotension in TAVR Patients · NA · recruiting
- NCT07338448 — Electrical Acupoint Stimulation on Gastric Reflux During I-gel Ventilation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04668534 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Air Force Military Medical University, China
- Last refreshed: 16 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04668534.
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