Last reviewed · How we verify

NCT04668534

Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Functional Dyspepsia

Status unknown NA Last updated 16 December 2020
What this trial tests

NA trial testing taVNS 10 in Functional Dyspepsia in 300 participants. Status unknown.

Timeline
1 November 2020
Primary endpoint
28 December 2021
28 March 2022

Quick facts

Lead sponsorAir Force Military Medical University, China
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposetreatment
Enrollment300
Start date1 November 2020
Primary completion28 December 2021
Estimated completion28 March 2022
Sites3 locations across China

Drugs / interventions tested

Conditions studied

Sponsor

Air Force Military Medical University, China

Who can join

Adults 18 to 65, any sex, with Functional Dyspepsia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with dyspeptic symptoms vary from 10% to 20% globally. Up to 70% of patients with dyspepsia who undergo endoscopy have unremarkable examination and are diagnosed with functional dyspepsia (FD). Given the lack of information related to its pathophysiology, the treatment is largely empirical and of limited efficacy. Previous small study showed therapeutic potential of transcutaneous auricular vagal nerve stimulation (taVNS) for FD. This study aims to investigate whether taVNS can improve the dyspeptic symptoms of patients with FD.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Transcutaneous Auricular Vagal Nerve Stimulation Is Effective for the Treatment of Functional Dyspepsia: A Multicenter, Randomized Controlled Study.
    Shi X, Zhao L, Luo H, Deng H, et al · · 2024 · cited 25× · PMID 37787432 · DOI 10.14309/ajg.0000000000002548
  2. 331: CLINICAL CHARACTERISTICS AND LONG-TERM OUTCOMES IN PATIENTS WITH CYCLIC VOMITING SYNDROME: A 12-YEAR EXPERIENCE AT A TERTIARY REFERRAL CENTER
    · 2022

Verify or expand the search:

Other recruiting trials for Functional Dyspepsia

Currently open trials in the same condition.

Other Air Force Military Medical University, China trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04668534.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing