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NCT04667195

Clinical Characteristics of Acutely Hospitalized Adults With Acute Pyelonephritis

Completed Last updated 14 September 2022
What this trial tests

trial testing Clinical assessment in Acute Pyelonephritis in 966 participants. Completed in 1 June 2022.

Timeline
1 March 2021
Primary endpoint
28 February 2022
1 June 2022

Quick facts

Lead sponsorUniversity of Southern Denmark
StatusCompleted
Study typeOBSERVATIONAL
Enrollment966
Start date1 March 2021
Primary completion28 February 2022
Estimated completion1 June 2022
Sites1 location across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

University of Southern Denmark

Who can join

18 and older, any sex, with Acute Pyelonephritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute pyelonephritis is an acute infection. Today the diagnosis is made primarily on the basis of unspecific clinical symptoms with flank tenderness combined with as a key clue. This study will investigate which clinical and paraclinical characteristics available within 4 hours of hospital stay, that describes the patients admitted in the emergency department with acute pyelonephritis the best.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Improved diagnostics of infectious diseases in emergency departments: a protocol of a multifaceted multicentre diagnostic study.
    Skjøt-Arkil H, Heltborg A, Lorentzen MH, Cartuliares MB, et al · · 2021 · cited 17× · PMID 34593497 · DOI 10.1136/bmjopen-2021-049606
  2. Urine Flow Cytometry and Dipstick Analysis in Diagnosing Bacteriuria and Urinary Tract Infections among Adults in the Emergency Department-A Diagnostic Accuracy Trial.
    Hertz MA, Johansen IS, Rosenvinge FS, Brasen CL, et al · · 2024 · cited 3× · PMID 38396451 · DOI 10.3390/diagnostics14040412
  3. The Diagnostic Accuracy of Procalcitonin, Soluble Urokinase-Type Plasminogen Activator Receptors, and C-Reactive Protein in Diagnosing Urinary Tract Infections in the Emergency Department-A Diagnostic Accuracy Study.
    Hertz MA, Johansen IS, Rosenvinge FS, Brasen CL, et al · · 2024 · cited 2× · PMID 38542009 · DOI 10.3390/jcm13061776
  4. Clinical characteristics, factors associated with urinary tract infection and outcome in acutely admitted patients with infection; an exploratory cross-sectional cohort study.
    Hertz MA, Skjøt-Arkil H, Heltborg A, Lorentzen MH, et al · · 2024 · cited 1× · PMID 38984294 · DOI 10.1016/j.heliyon.2024.e32815
  5. Prediction of infection in the emergency department-a machine learning model.
    Søgaard SN, Skjøt-Arkil H, Mogensen CB, Rosenvinge FS, et al · · 2026 · PMID 42147041 · DOI 10.3389/frai.2026.1812692
  6. Clinical characteristics and diagnostic accuracy of preliminary diagnoses in adults with infections in Danish emergency departments: a multicentre combined cross-sectional and diagnostic study.
    Skjøt-Arkil H, Cartuliares MB, Heltborg A, Lorentzen MH, et al · · 2024 · PMID 39638587 · DOI 10.1136/bmjopen-2024-090259

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