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NCT04666103
Function Integrity of Neck Anatomy in Thyroid Surgery
NA trial testing Intraoperative thermal ablation in Thyroid Carcinoma in 1,264 participants. Currently enrolling.
31 December 2021
Quick facts
| Lead sponsor | Wuhan University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 1,264 |
| Start date | 11 December 2020 |
| Primary completion | 31 December 2021 |
| Estimated completion | 12 December 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Intraoperative thermal ablation
Conditions studied
- Thyroid Carcinoma — all drugs for Thyroid Carcinoma →
- Thyroid Nodule (Benign) — all drugs for Thyroid Nodule (Benign) →
- Ablation; Retina — all drugs for Ablation; Retina →
Sponsor
Wuhan University
Who can join
Adults 18 to 75, any sex, with Thyroid Carcinoma or Thyroid Nodule (Benign). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment. Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04666103
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Thyroid Carcinoma
Currently open trials in the same condition.
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- NCT07473518 — Thyroid Carcinoma in Cancer Patients Undergoing Radiotherapy · recruiting
- NCT07072143 — An International Study on Pediatric Patients With Rare Tumors. · recruiting
- NCT06146764 — CEUS Improves the Diagnostic Performance of SRSS of Thyroid Carcinoma · recruiting
Other Wuhan University trials
Trials by the same sponsor.
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- NCT06971705 — fMRI Study on Cerebral Localization and Network Mechanisms of rTMS in Chronic Ankle Instability Treatment · NA · active not recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04666103 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wuhan University
- Last refreshed: 14 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04666103.
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