NCT04665245 is a clinical trial in Covid19, sponsored by University of Iowa.

Who is sponsoring NCT04665245?

NCT04665245 is sponsored by University of Iowa.

Is NCT04665245 still recruiting?

NCT04665245 is currently completed. Last updated 26 January 2026.

Are results published for NCT04665245?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2026-01-26 · How we verify

NCT04665245

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Symptom-Based Markers for COVID-19 Transmission

Completed Results posted Last updated 26 January 2026

What this trial tests

trial in Covid19 in 214 participants. Completed in 19 May 2021.

Timeline

15 December 2020

Primary endpoint
19 May 2021

19 May 2021

Quick facts

Lead sponsor	University of Iowa
Status	Completed
Study type	OBSERVATIONAL
Enrollment	214
Start date	15 December 2020
Primary completion	19 May 2021
Estimated completion	19 May 2021
Sites	1 location across United States

Conditions studied

Covid19 — all drugs for Covid19 →

Sponsor

University of Iowa

Who can join

Adults 18 to 100, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Body Temperature Primary · 10 days

Body temperature taken each morning and evening throughout COVID-19 infection period.

Group	Value	95% CI
COVID-19 Positive Patients	98.1	± 0.85

COVID-19 Symptoms Primary · 10 days

Any symptoms experienced throughout COVID-19 infection period (aches, cough, decreased sense of taste and/or smell, diarrhea, difficulty breathing, headache, nausea, runny nose, sore throat, shortness of breath).

Group	Value	95% CI
COVID-19 Positive Patients	956
COVID-19 Positive Patients	1532
COVID-19 Positive Patients	1669
COVID-19 Positive Patients	305

Sponsor's own description

In this study, COVID-19 positive patients will be added to a bidirectional texting program to receive daily surveys about their symptoms with the infection. This data will further the understanding of COVID-19 symptom development throughout the infection period, as well as how those symptoms vary at different points of the day. This study will be a single cohort, observational study of COVID-19 patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Covid19

Currently open trials in the same condition.

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NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting

Other University of Iowa trials

Trials by the same sponsor.

NCT07224269 — Effect of Terazosin on ATP Levels in People With Amyotrophic Lateral Sclerosis · EARLY_PHASE1 · not yet recruiting
NCT07244809 — Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adve · NA · recruiting
NCT07097961 — Paediatric Post-TB Pulmonary Rehab Study · NA · recruiting
NCT06951594 — Robotic-Assisted Versus Manual Electrode Array Insertion · NA · recruiting
NCT06710119 — Effect of Custom Dynamic Orthoses on Forefoot Loading · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04665245 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Iowa
Last refreshed: 26 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04665245.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing