NCT04663594 (O-ACEPOP) is a NA clinical trial of WofB in Depression, sponsored by University of Oxford.

Who is sponsoring NCT04663594?

NCT04663594 is sponsored by University of Oxford.

What drugs are being tested in NCT04663594?

Interventions in NCT04663594: WofB, Ashmolean Website.

What condition does NCT04663594 study?

NCT04663594 studies Depression, Anxiety.

Is NCT04663594 still recruiting?

NCT04663594 is currently completed. Last updated 6 May 2022.

Last reviewed 2022-05-06 · How we verify

NCT04663594: O-ACEPOP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Online Culture for Mental Health in People Aged 16-24

Completed NA Last updated 6 May 2022

What this trial tests

NA trial testing WofB in Depression in 463 participants. Completed in 10 February 2021.

Timeline

4 December 2020

Primary endpoint
10 February 2021

10 February 2021

Quick facts

Lead sponsor	University of Oxford
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	463
Start date	4 December 2020
Primary completion	10 February 2021
Estimated completion	10 February 2021
Sites	1 location across United Kingdom

Drugs / interventions tested

WofB
Ashmolean Website

Conditions studied

Depression — all drugs for Depression →
Anxiety — all drugs for Anxiety →

Sponsor

University of Oxford

Who can join

Adults 16 to 24, any sex, with Depression or Anxiety. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

O-ACE POP is a randomised controlled trial of an online cultural experience named Ways of Being, compared to a typical museum website (the Ashmolean Museum). The primary aim is to compare these two interventions by efficacy on mood, distress (depression and anxiety), flourishing and investigate potential mechanisms of action, as well as the feasibility of a larger scale RCT.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

A cultural experience to support mental health in people aged 16-24 during the COVID-19 pandemic compared to a typical museum website: study protocol of an online randomised controlled trial.
Syed Sheriff RJ, Vuorre M, Riga E, Przybylski AK, et al · · 2021 · cited 5× · PMID 34294126 · DOI 10.1186/s13063-021-05441-z
Online cultural experiences for mental health in people aged 16-24: a qualitative analysis of multisource data from a randomised controlled trial.
Syed Sheriff R, Riga E, O'Dell B, Chandler L, et al · · 2026 · PMID 42049312 · DOI 10.1136/bmjopen-2025-105217
An Online Cultural Experience for Mental Health in People Aged 16-24 Compared to a Typical Museum Website: A Randomised Controlled Trial
Sheriff RS, Vuorre M, Riga E, Przybylski A, et al · · 2021 · DOI 10.2139/ssrn.3934229
A Cultural Experience to support Mental Health in People Aged 16-24 During COVID-19 Compared to a Typical Museum Website: Study Protocol of an Online Randomised Controlled Trial
Sheriff RS, Vuorre M, Riga E, Przybylski AK, et al · · 2021 · DOI 10.21203/rs.3.rs-181910/v1

Verify or expand the search:

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Other University of Oxford trials

Trials by the same sponsor.

NCT05380388 — A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) · Phase 2 · not yet recruiting
NCT07470424 — A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults · Phase 1 · not yet recruiting
NCT07345910 — Environment, Pathogens, and Host Interactions in Melioidosis · not yet recruiting
NCT07434973 — Stratification and Treatment in Early Psychosis Study - PROMOTE · Phase 3 · not yet recruiting
NCT07460401 — 'Do Patient Characteristics Associate With Poor Outcome With Femoral Acetabular Impingement Syndrome (FAIS) Following Ph · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04663594 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Oxford
Last refreshed: 6 May 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04663594.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing