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NCT04663490
Neutrophil to Lymphocyte Ratio as a Predictor of Complicated Acute Diverticulitis
trial testing Neutrophil to Lymphocyte Ratio in Acute Diverticulitis in 325 participants. Completed in 1 January 2020.
1 January 2018
Quick facts
| Lead sponsor | Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 325 |
| Start date | 1 January 2013 |
| Primary completion | 1 January 2018 |
| Estimated completion | 1 January 2020 |
| Sites | 1 location across Argentina |
Drugs / interventions tested
- Neutrophil to Lymphocyte Ratio — full drug profile →
Conditions studied
- Acute Diverticulitis — all drugs for Acute Diverticulitis →
Sponsor
Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba
Who can join
Adults 18 to 92, any sex, with Acute Diverticulitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Various biomarkers have been studied to predict the severity of acute diverticulitis (AD), such as the leukocyte count and CRP, which are useful but lack sufficient sensitivity. The neutrophil-lymphocyte ratio (NLR) has been identified as a new inflammatory biomarker in several abdominal pathologies. However, few studies determine its association with the severity of AD. The objective of the present study was to determine the utility and diagnostic precision of NLR in complicated acute diverticulitis (cAD). Material and methods: Descriptive, retrospective and analytical study. Patients older than 18 years with a diagnosis of AD were included, from 2013 - 2018. Demographic variables, days of hospitalization, leukocyte count, neutrophils, lymphocytes, ESR, CRP, and NLR were analyzed. The sensitivity and specificity for the diagnosis of cAD were determined using ROC curves.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Neutrophil-to-lymphocyte ratio as a predictor of complicated acute diverticulitis: A retrospective cohort study.
Palacios Huatuco RM, Pantoja Pachajoa DA, Bruera N, Pinsak AE, et al · · 2021 · cited 10× · PMID 33643646 · DOI 10.1016/j.amsu.2021.01.076
Verify or expand the search:
- PubMed search for NCT04663490
- Europe PMC full search
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Related trials
Other Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba trials
Trials by the same sponsor.
- NCT04703400 — Analysis of the Impact on Surgical Residency Programs in Times of Pandemic in Argentina · completed
- NCT04673110 — Neutrophil-to-lymphocyte Ratio vs C-reactive Protein as Early Predictors of Anastomotic Leakage After Colorectal Surgery · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04663490 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba
- Last refreshed: 11 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04663490.
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