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NCT04660825
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
NA trial testing A resistance band exercise programme in Osteoporosis in 41 participants. Completed in 31 January 2020.
31 December 2019
Quick facts
| Lead sponsor | Loughborough University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 41 |
| Start date | 1 October 2018 |
| Primary completion | 31 December 2019 |
| Estimated completion | 31 January 2020 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- A resistance band exercise programme
- Control
Conditions studied
- Osteoporosis — all drugs for Osteoporosis →
- Osteoporotic Fracture of Vertebra — all drugs for Osteoporotic Fracture of Vertebra →
- Postural, Thoracic Kyphosis — all drugs for Postural, Thoracic Kyphosis →
Sponsor
Loughborough University
Who can join
Adults 60 to 80, female only, with Osteoporosis or Osteoporotic Fracture of Vertebra. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture. Unfortunately, not all exercises strengthen bone. Exercises that do work (e.g. heavy weight lifting) are not popular with women at risk of osteoporosis. The investigators will develop a feasible exercise programme that can be done at a community centre or at home, using resistance bands. The investigators will involve women in designing the programme and incorporate strategies to support behaviour change. The investigators will then examine whether the programme improves bone density, posture or muscle strength in eighty women. Half the women, chosen at random, will take up exercise whilst the remaining half act as a control group. The investigators will take bone scans to determine bone density, and measure spinal curvature and strength, before and after the six- month programme. Findings will be useful in making recommendations as to which types of exercise increase spine bone density and will help to design future research on maximising vertebral strength. If significant benefits are seen, the investigators will develop resources such as booklets and videos so that the intervention can be widely available.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04660825
- Europe PMC full search
- ASCO Meeting Library
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- bioRxiv preprints
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Other Loughborough University trials
Trials by the same sponsor.
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- NCT06682897 — Simplified Tai Chi Exercises to Improve Function in People With Chronic Ankle Instability · NA · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04660825 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Loughborough University
- Last refreshed: 9 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04660825.
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