NCT04660175

The Efficacy and Safety of Non-resistance Manual Therapy in Inpatients With Acute Neck Pain Caused by Traffic Accidents: a Randomised Controlled Trial

Completed NA Last updated 15 May 2023

What this trial tests

NA trial testing non-resistance therapy in Whiplash Injury of Cervical Spine in 120 participants. Completed in 26 July 2022.

Timeline

30 November 2020

Primary endpoint
13 May 2022

26 July 2022

Quick facts

Lead sponsor	Jaseng Medical Foundation
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	120
Start date	30 November 2020
Primary completion	13 May 2022
Estimated completion	26 July 2022
Sites	1 location across South Korea

Drugs / interventions tested

• non-resistance therapy
• acupuncture — full drug profile →
• chuna
• pharmacoacupuncture
• Korean herbal medicine — full drug profile →

Conditions studied

• Whiplash Injury of Cervical Spine — all drugs for Whiplash Injury of Cervical Spine →

Sponsor

Jaseng Medical Foundation

Who can join

Adults 19 to 70, any sex, with Whiplash Injury of Cervical Spine. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Non-resistance therapy is a combination of muscle compression relaxation technique and joint mobilization in patients with acute neck pain caused by traffic accidents. This study is to evaluate the effectiveness and safety of non-resistance therapy for pain and function problems in patients complaining of acute neck pain induced by traffic accidents.

So, investigators conduct a randomized controlled trials to verify the effectiveness and safety of non-resistance therapy. From December 2020 to May 2021, investigators recruit 120 inpatients who are suffered from acute neck pain with the numeric rating scale(NRS) over 5 by traffic accident(TA).

The Korean medical treatment group(n=60) receives daily acupuncture, herbal medicine, and chuna treatment as inpatient treatment from hospitalization until discharge. For the non-resistance therapy group(n=60), the korean medical treatment is performed in the same manner, but additional non-resistance therapy is performed once a day from the 2nd day to the 5th day of hospitalization.

Baseline is the time point before treatment for non-resistance therapy on the second day of hospitalization, and the primary endpoint is the time point after treatment on the 5th day (v5) after hospitalization.

For these two groups, investigators compare NRS(Numeric Rating Scale), Visual Analogue Scale(VAS), Range Of Motion(ROM), Neck Disability Index(NDI), the 12-Item Short Form Health Survey(SF-12), and PTSD Checklist for DSM(Diagnostic and Statistical Manual of Mental Disorders, DSM)-5(PCL-5).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. The efficacy and safety of non-resistance manual therapy in inpatients with acute neck pain caused by traffic accidents: A randomized controlled trial.
   Kim S, Kyeong DH, Kim MK, Kim CY, et al · · 2022 · cited 2× · PMID 35665724 · DOI 10.1097/md.0000000000029151
2. Effectiveness and safety of manual therapy for inpatients with traffic accident-induced acute neck pain: A randomized controlled trial.
   Choi SW, Kim KH, Yoon JY, Lee SW, et al · · 2026 · PMID 41298158 · DOI 10.1016/j.joim.2025.10.008