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Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery
Direct laryngoscopy (DL) procedure is typically done under general anaesthesia as a day case. It is a short but irritating.Various drugs and drug combinations have been used to attenuate stress response to DL.Administrating nebulized form of drugs can be effective with less systemic side effects. The primary outcome of this study is to compare the effect of premedication with nebulized lidocaine, dexmedetomidine, combination of both to placebo on haemodynamic response during DL procedures.
Details
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | PHASE4 |
| Status | COMPLETED |
| Enrolment | 180 |
| Start date | Sat Dec 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Jul 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Hemodynamic Instability
Interventions
- Nebulized Lidocaine
- Nebulized dexmedetomidine
- Nebulized lidocaine and dexmedetomidine
- Placebo
Countries
Egypt