Last reviewed · How we verify
NCT04656340: IMPPPORT
Complementary and Integrative Pain Therapies and Functional Restoration (IMPPPORT) Trial)
NA trial testing non-medication, non-interventional therapies in Chronic Pain in 210 participants. Completed in 2 April 2019.
2 April 2019
Quick facts
| Lead sponsor | Madigan Army Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 210 |
| Start date | 9 December 2015 |
| Primary completion | 2 April 2019 |
| Estimated completion | 2 April 2019 |
Drugs / interventions tested
- non-medication, non-interventional therapies
Conditions studied
- Chronic Pain — all drugs for Chronic Pain →
Sponsor
Madigan Army Medical Center
Who can join
Adults 18 to 85, any sex, with Chronic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate the benefit of a complementary and integrative health (CIH) pain management program when added to standard rehabilitative care (SC) compared to SC alone prior to an intensive functional restoration (FR) program in a population of active duty service members. In addition the study aims to identify factors that predict improvement in pain impact following treatment, and to determine the proportion of participants who experience clinically meaningful response. SC included physical and occupational therapy. CIH included chiropractic, acupuncture, yoga and foam roller instruction. Both treatment groups also received education about pain psychology. Participants were randomly assigned to a 3-week course of either SC alone or CIH combined with SC prior to a 3-week course of FR. Outcomes were collected at baseline, at end of stage 1, and post-FR. Outcomes included patient-reported and provider-determined measures.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Estimating minimal important change of the National Institutes of health research task force impact score using computer adaptive measures: a secondary analysis of two randomized clinical trials in a military population with chronic pain.
Flynn DM, Burke LA, Steffen AD, Ransom JC, et al · · 2025 · cited 3× · PMID 39934777 · DOI 10.1186/s12891-025-08378-5 -
The Role of Psychological Factors in Chronic Pain Treatment Outcomes in the Military.
Eaton LH, Flynn DM, Steffen AD, Doorenbos AZ. · · 2023 · cited 3× · PMID 36653221 · DOI 10.1016/j.pmn.2022.12.007 -
Use of a treadmill, lift, and carry battery as a composite functional performance test: analysis of data from a pragmatic randomized controlled trial in a military population participating in a functional restoration program.
Snow T, Burke L, Sanford DC, Mathew A, et al · · 2024 · cited 2× · PMID 36282735 · DOI 10.1080/09593985.2022.2135149 -
Predictors of Sustained Response to Functional Restoration in a Military Population.
Flynn DM, Burke LA, Ransom JC, McQuinn HM, et al · · 2023 · cited 1× · PMID 37948256 · DOI 10.1093/milmed/usac432
Verify or expand the search:
- PubMed search for NCT04656340
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Pain
Currently open trials in the same condition.
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- NCT07103135 — Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling · Phase 1 · recruiting
- NCT06219408 — CIH Stepped Care for Co-occurring Chronic Pain and PTSD · NA · recruiting
- NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting
Other Madigan Army Medical Center trials
Trials by the same sponsor.
- NCT07335276 — Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI) · NA · not yet recruiting
- NCT05190341 — Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram · Phase 4 · terminated
- NCT04704297 — Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial · Phase 4 · recruiting
- NCT04547413 — STI/HIV Intervention Behavioral Intervention Program · NA · completed
- NCT04959318 — Precision Nutrition Impact on Health-Related Behavior Change · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04656340 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Madigan Army Medical Center
- Last refreshed: 24 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04656340.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing