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NCT04655105
Evaluation of Post Operative Pain Following Reciprocating and Rotary Heat-treated NiTi Instrumentation of Root Canals: a Randomized Controlled Clinical Trial
NA trial testing root canal rotary files in Root Canal Infection in 220 participants. Status unknown.
3 May 2021
Quick facts
| Lead sponsor | Tamil Nadu Dr.M.G.R.Medical University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 220 |
| Start date | 3 January 2021 |
| Primary completion | 3 May 2021 |
| Estimated completion | 3 June 2021 |
| Sites | 1 location across India |
Drugs / interventions tested
- root canal rotary files
Conditions studied
- Root Canal Infection — all drugs for Root Canal Infection →
Sponsor
Tamil Nadu Dr.M.G.R.Medical University
Who can join
Adults 15 to 70, any sex, with Root Canal Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present clinical evaluation was planned for comparing the post-operative pain incidence in maxillary premolar teeth with acute irreversible pulpitis treated by recently introduced heat treated TruNatomy TM and other widely studied heat-treated files Hyflex EDM, Protaper Gold and one heat-treated reciprocating EdgeFile in single-visit root canal treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Evaluation of postoperative pain with new heat-treated rotary and reciprocating nickel-titanium files: A randomized controlled clinical trial.
Valliappan CT, Rahul B, Gabriel EM, Sherwood IA, et al · · 2023 · cited 5× · PMID 37205884 · DOI 10.4103/jcd.jcd_566_22
Verify or expand the search:
- PubMed search for NCT04655105
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Root Canal Infection
Currently open trials in the same condition.
- NCT07206108 — Clinical Trial of Modified Endocrown and Personalized Post-core and Crown for Large-area Tooth Defects After Root Canal · NA · recruiting
- NCT07048028 — Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial) · NA · recruiting
- NCT06811636 — Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars · NA · active not recruiting
- NCT06949176 — Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal · NA · active not recruiting
- NCT04527705 — Outcome of Endodontic Retreatment in One or Two Visits · NA · recruiting
Other Tamil Nadu Dr.M.G.R.Medical University trials
Trials by the same sponsor.
- NCT04248803 — Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite · NA · completed
- NCT04250519 — Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant · Phase 1 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04655105 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tamil Nadu Dr.M.G.R.Medical University
- Last refreshed: 30 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04655105.
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