NCT04653610 (Saturne-HIV) is a clinical trial in Hiv, sponsored by University Hospital, Ghent.

Who is sponsoring NCT04653610?

NCT04653610 is sponsored by University Hospital, Ghent.

Is NCT04653610 still recruiting?

NCT04653610 is currently recruiting now. Last updated 8 February 2024.

Last reviewed 2024-02-08 · How we verify

NCT04653610: Saturne-HIV

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sequential Analysis Before and After Treatment Initiation to Unravel the Role of Naturally Occurring Extracellular Vesicles in HIV Infection

Recruiting now Last updated 8 February 2024

What this trial tests

trial in Hiv in 105 participants. Currently enrolling.

Timeline

27 January 2021

Primary endpoint
1 January 2027

1 January 2027

Quick facts

Lead sponsor	University Hospital, Ghent
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	105
Start date	27 January 2021
Primary completion	1 January 2027
Estimated completion	1 January 2027
Sites	1 location across Belgium

Conditions studied

Hiv — all drugs for Hiv →

Sponsor

University Hospital, Ghent

Who can join

Adults 18 to 65, any sex, with Hiv. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to evaluate the role of extracellular vesicles in HIV-infection, by determining the expression profile and content of EVs before and after treatment initiation in HIV-infected patients, through extensive blood and tissue sampling (leukapheresis, stool sampling and colon biopsies). A one-time sampling (blood, stool, colon biopsies) will also be performed in HIV-seronegative healthy volunteers to confirm that results found in HIV-infected patients are related to the disease.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

The roles of extracellular vesicles in the immune system.
Buzas EI. · · 2023 · cited 811× · PMID 35927511 · DOI 10.1038/s41577-022-00763-8
From stem cells to extracellular vesicles: a new horizon in tissue engineering and regenerative medicine.
Arbade G, Jose JV, Gulbake A, Kadam S, et al · · 2024 · cited 5× · PMID 38933869 · DOI 10.1007/s10616-024-00631-4
Evolution of the HIV-1 integration site landscape and inducible reservoir in early-treated people.
Struyve T, Pardons M, De Clercq J, Termote L, et al · · 2025 · cited 1× · PMID 41289275 · DOI 10.1371/journal.ppat.1013702

Verify or expand the search:

Other recruiting trials for Hiv

Currently open trials in the same condition.

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Other University Hospital, Ghent trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04653610 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Ghent
Last refreshed: 8 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04653610.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing