NCT04650412 (TMIRA) is a NA clinical trial of Bundle of comorbidities care in Acute Hypercapnic Respiratory Failure, sponsored by CTU.

Who is sponsoring NCT04650412?

NCT04650412 is sponsored by CTU.

What drugs are being tested in NCT04650412?

Interventions in NCT04650412: Bundle of comorbidities care.

What condition does NCT04650412 study?

NCT04650412 studies Acute Hypercapnic Respiratory Failure.

Is NCT04650412 still recruiting?

NCT04650412 is currently terminated. Last updated 12 May 2023.

Last reviewed 2023-05-12 · How we verify

NCT04650412: TMIRA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Integrated Care of Co-morbidities vs Standard Care After AHRF in the Intensive Care Unit

Terminated NA Last updated 12 May 2023

What this trial tests

NA trial testing Bundle of comorbidities care in Acute Hypercapnic Respiratory Failure in 188 participants. Terminated before completion.

Timeline

28 May 2018

Primary endpoint
31 July 2022

31 July 2022

Quick facts

Lead sponsor	CTU
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	188
Start date	28 May 2018
Primary completion	31 July 2022
Estimated completion	31 July 2022
Sites	3 locations across France, Switzerland

Drugs / interventions tested

Bundle of comorbidities care

Conditions studied

Acute Hypercapnic Respiratory Failure — all drugs for Acute Hypercapnic Respiratory Failure →

Sponsor

CTU — full company profile →

Who can join

18 and older, any sex, with Acute Hypercapnic Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will assess the potential benefit of implementing a complex bundle of interventions to treat important - often unrecognized - comorbidities in patients surviving an episode of Acute Hypercapnic Respiratory Failure (AHRF). This study will also provide a comparative analysis of the costs and health consequences of two alternative strategies to inform decision making about healthcare. All interventions are individually evidence-based and seem sound to hypothesize that implementing such interventions might improve patient's outcome and reduce the financial burder of repeated hospitalization in AHRF survivors.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Acute Hypercapnic Respiratory Failure

Currently open trials in the same condition.

NCT06374589 — Closed-Loop O2 Use During High Flow Oxygen Treatment of Critical Care Adult Patients (CLOUDHFOT) · NA · recruiting
NCT05011877 — The Simplify Project · recruiting
NCT03033251 — High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04650412 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by CTU
Last refreshed: 12 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04650412.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing