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NCT04648072: TRUE KnORTH
How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study.
NA trial testing Adductor Canal Block in Knee Osteoarthritis in 60 participants. Completed in 1 December 2021.
30 November 2021
Quick facts
| Lead sponsor | Health Sciences North Research Institute |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 4 November 2020 |
| Primary completion | 30 November 2021 |
| Estimated completion | 1 December 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Adductor Canal Block — full drug profile →
- Periarticular Injection — full drug profile →
Conditions studied
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Arthritis Knee — all drugs for Arthritis Knee →
- Knee Disease — all drugs for Knee Disease →
- Opioid Use — all drugs for Opioid Use →
Sponsor
Health Sciences North Research Institute
Who can join
18 and older, any sex, with Knee Osteoarthritis or Arthritis Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The use of periarticular injection and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing total knee arthroplasty. The aim of this study is to investigate whether combining these two techniques have an added benefit, compared to periarticular injection alone, with respect to quality of recovery, functional return, discharge readiness, and short and long term post-operative narcotic use.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04648072
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Adductor Canal Block
Trials testing the same drug.
- NCT07360392 — BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia · NA · not yet recruiting
- NCT07288970 — ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty · NA · recruiting
- NCT06837844 — Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty · NA · recruiting
- NCT06586840 — The Effect of Adding an IPACK Block to the Adductor Canal Block on Total Knee Arthroplasty Surgery · recruiting
- NCT06402110 — Femoral Triangle Block Versus Adductor Canal Block in Arthroscopic Anterior Cruciate Ligament Reconstruction · NA · completed
Other recruiting trials for Knee Osteoarthritis
Currently open trials in the same condition.
- NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
- NCT05823727 — Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing Afte · NA · recruiting
- NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
- NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
- NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting
Other Health Sciences North Research Institute trials
Trials by the same sponsor.
- NCT05983354 — Oral Medications for the Management of Acute Migraine Headache in the Emergency Department · NA · unknown
- NCT04504474 — Network Analysis of Adult MDD and ADHD · unknown
- NCT04604574 — Evaluating the Integration of Indigenous Healing With Principals of Seeking Safety for Treatment of Indigenous Patients · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04648072 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Health Sciences North Research Institute
- Last refreshed: 6 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04648072.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing