Who is sponsoring NCT04647305?

NCT04647305 is sponsored by University of Los Andes, Columbia.

What drugs are being tested in NCT04647305?

Interventions in NCT04647305: Closed face shield with Surgical face mask use, Surgical face mask use only.

What condition does NCT04647305 study?

NCT04647305 studies SARS-CoV-2 Infection.

Is NCT04647305 still recruiting?

NCT04647305 is currently completed. Last updated 27 April 2021.

Last reviewed 2021-04-27 · How we verify

NCT04647305: COVPROSHIELD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness and Adherence to Closed Face Shields to Prevent COVID-19 Transmission

Completed NA Last updated 27 April 2021

What this trial tests

NA trial testing Closed face shield with Surgical face mask use in SARS-CoV-2 Infection in 233 participants. Completed in 4 March 2021.

Timeline

16 January 2021

Primary endpoint
4 March 2021

4 March 2021

Quick facts

Lead sponsor	University of Los Andes, Columbia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	233
Start date	16 January 2021
Primary completion	4 March 2021
Estimated completion	4 March 2021
Sites	1 location across Colombia

Drugs / interventions tested

Closed face shield with Surgical face mask use
Surgical face mask use only

Conditions studied

SARS-CoV-2 Infection — all drugs for SARS-CoV-2 Infection →

Sponsor

University of Los Andes, Columbia

Who can join

18 and older, any sex, with SARS-CoV-2 Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A non-inferiority randomized controlled trial that aims to determine the effectiveness and adherence of the use of closed-face shields and surgical face masks in comparison with the use of surgical face masks for the prevention of SARS-CoV-2 infection in working adults in the city of Bogota, Colombia.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Randomized trials on non-pharmaceutical interventions for COVID-19: a scoping review.
Hirt J, Janiaud P, Hemkens LG. · · 2022 · cited 24× · PMID 35086864 · DOI 10.1136/bmjebm-2021-111825
Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings.
Pizarro AB, Persad E, Durao S, Nussbaumer-Streit B, et al · · 2022 · cited 17× · PMID 35514111 · DOI 10.1002/14651858.cd015112.pub2
Effectiveness and adherence to closed face shields in the prevention of COVID-19 transmission: a non-inferiority randomized controlled trial in a middle-income setting (COVPROSHIELD).
Varela AR, Gurruchaga AP, Restrepo SR, Martin JD, et al · · 2022 · cited 5× · PMID 35987694 · DOI 10.1186/s13063-022-06606-0
Randomized trials on non-pharmaceutical interventions for COVID-19 as of August 2021: a meta-epidemiological analysis
Hirt J, Janiaud P, Hemkens LG. · · 2021 · DOI 10.1101/2021.08.20.21261687

Verify or expand the search:

Other recruiting trials for SARS-CoV-2 Infection

Currently open trials in the same condition.

NCT07079670 — Safety and Immunogenicity of NVX-CoV2705 · Phase 3 · active not recruiting
NCT05697068 — Intervention to Prevent Household and Community Spread of COVID-19 Among Latinos · NA · active not recruiting
NCT05172011 — Understanding the Long-term Impact of COVID on Children and Families · active not recruiting
NCT05141058 — T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients · Phase 1 · recruiting
NCT05046470 — SARS-CoV-2 Transmission in Belgian Primary Schools of the Federation Wallonia - Brussels: An Epidemiological Pilot Study · active not recruiting

Other University of Los Andes, Columbia trials

Trials by the same sponsor.

NCT07148531 — Caregiver Mental Health and Early Childhood Development in Conflict-Affected Settings · NA · active not recruiting
NCT06579456 — Evaluation in a Multimodal Structured Curriculum of Laparoscopic Surgery · NA · completed
NCT04647318 — Physiological Response to Self-compassion Versus Relaxation · NA · completed
NCT03512665 — Evaluation of the Impact of a Nutritional Supplement Made of Vegetable Oils in People at Risk of Diabetes · NA · completed
NCT03502252 — Experimental Evaluation of Semillas de Apego · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04647305 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Los Andes, Columbia
Last refreshed: 27 April 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04647305.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing