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NCT04646629
Effect of Electroacupuncture on Sepsis-induced Intestinal Dysfunction
NA trial testing electroacupuncture treatment in Sepsis in 30 participants. Status unknown.
31 December 2021
Quick facts
| Lead sponsor | Jianbo Yu |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 23 November 2020 |
| Primary completion | 31 December 2021 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- electroacupuncture treatment
- sham electroacupuncture treatment
Conditions studied
- Sepsis — all drugs for Sepsis →
- Intestinal Dysfunction — all drugs for Intestinal Dysfunction →
Sponsor
Jianbo Yu
Who can join
Adults 18 to 90, any sex, with Sepsis or Intestinal Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
1. Title: Effect of electroacupuncture on sepsis-induced intestinal dysfunction 2. Research center: single center 3. The Design of the study: Randomized, double-blind, controlled study 4. The population of the study: The patients over 18 years that met the criteria of sepsis3.0 and with AGI grade II or above are enrolled in the study 5. Sample size: Enroll 60 patients (30patients in each group) 6. Interventions: Participants in the treatment group underwent 60 minutes acupuncture (0.30mm×70mm) at ST36 (Zusanli) and ST37 (Shangjuxu) twice a day for seven days. After"Deqi",electroacupuncture stimulation apparatus (HANS G6805-2, Huayi Co, Shanghai, China) is connected and maintained the end of treatment. Participants in the control group received shallow needling (0.30mm×25mm) at ST36 and ST37(nonacupoints located 1 inch beside acupoints, about 20mm). Specifically, the depth of needle insertion into nonacupoints is 3-5mm and avoided manual stimulation and no "Deqi" without actual current output. 7. The aim of the research: To investigate the effect of electroacupuncture on sepsis-induced intestinal dysfunction. 8. Outcome# 1) Primary outcome: The intestinal function indicators including: 1) Clinical symptoms: bowel sounds, intra-abdominal pressure, time to first exhaust/defecation, daily tolerable enteral nutrition 2) Intestinal motility indicators: the levels of serum motilin and gastrin 3) Intestinal barrier indicators: the levels of serum diamine oxidase (DAO), D-lactic acid and I-FABP 2)Secondary outcome# Duration of mechanical ventilation in patients with endotracheal intubation on ICU admission; Length of stay in ICU and Length of stay in hospital; 30-day life quality and cognitive function after surgery; All-cause 28-day mortality. 9. The estimated duration of the study#1-2years.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04646629
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Related trials
Other trials of electroacupuncture treatment
Trials testing the same drug.
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- NCT04813510 — Effect of Electroacupuncture on SAP With MODS · NA · unknown
- NCT03606941 — Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery · NA · completed
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Currently open trials in the same condition.
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Other Jianbo Yu trials
Trials by the same sponsor.
- NCT04813510 — Effect of Electroacupuncture on SAP With MODS · NA · unknown
- NCT05053763 — The 90% Effective Dose of Remimazolam for Duodenoscopy Insertion During ERCP With Alfentanil 10µg/kg · NA · unknown
- NCT04647201 — Study of Biomarkers in Patients of Sepsis Complicated With Gastrointestinal Dysfunction · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04646629 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jianbo Yu
- Last refreshed: 30 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04646629.
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