NCT04645992

Effect of Combining Yoga to TENS on Diabetic Glaucoma

Status unknown NA Last updated 27 November 2020

What this trial tests

NA trial testing active TENS in Diabetes Mellitus in 80 participants. Status unknown.

Timeline

20 November 2020

Primary endpoint
1 February 2021

1 February 2021

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	80
Start date	20 November 2020
Primary completion	1 February 2021
Estimated completion	1 February 2021
Sites	1 location across Egypt

Drugs / interventions tested

• active TENS
• sham TENS

Conditions studied

• Diabetes Mellitus — all drugs for Diabetes Mellitus →
• Glaucoma — all drugs for Glaucoma →

Sponsor

Cairo University

Who can join

Adults 50 to 70, any sex, with Diabetes Mellitus or Glaucoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intraocular pressure (IOP) is maintained by a balance between aqueous production and outflow with an imbalance leading to elevated eye pressure. Very high levels of IOP will subject retinal cells to mechanical stress. In addition to mechanical injury, IOP elevation can impair ocular blood flow reducing perfusion pressure to retinal neurons. Long-term vascular and mechanical stresses can produce further injury at the optic nerve.

Elevated intraocular pressure (IOP) or ocular hypertension (OHT) is the only well-established modifiable risk factor for primary open-angle glaucoma (POAG), the most common form of glaucoma. Glaucoma is a class of optic neuropathy. It is main leading cause of blindness.

Glaucoma is classified on the basis of anatomic features as open angle (where the anterior chamber angle of the eye remains open) and angle-closure (with closure of the anterior chamber angle). Glaucoma is considered primary if the eye has no preexisting disease. Secondary forms of glaucoma are caused by various ocular or systemic diseases such as pigment dispersion syndrome and ocular trauma.

It seems reasonable to consider that a longer duration of diabetes mellitus (DM) with a prolonged insult to the retina and optic nerve via vascular, glial, and neuronal factors would be associated with a higher risk of OAG.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.