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Sleeve Gastrectomy: Outcome, Morbidity and Mortality. A Multicentric Retrospective Trial (PSICHE)

NCT04643262 ENROLLING_BY_INVITATION

Laparoscopic sleeve gastrectomy (LSG) is currently the most frequent primary bariatric procedure performed worldwide. LSG is a safe and effective technique in terms of excess weight loss and it is, moreover, a powerful metabolic operation that activates significant hormonal pathways that lead to changes in eating behavior, glycemic control and intestinal functions.Regarding a technical point of view, LSG might be considered a time saving procedure for the absence of intestinal anastomosis. The most frequent and sometimes dangerous complications are leaking, hemorrhage, splenic injury, stenosis and Gastro-Esophageal Reflux Disease (GERD). Despite its established efficacy and safety, dispute still exists on the optimal conduction of LSG operative technique: bougie size, distance of resection margin from the pylorus, the shape of section at the gastroesophageal junction, staple line reinforcement and intraoperative leak testing are among the most controversial issues . Thus, the primary aim of the present retrospective multicentric study is to evaluate intra and peri-operatory (\< 30 days) and post-operative (\> 30 days) morbidity and mortality rates of patients undergone LSG, and the correlation of the latter rates with different surgical measures. Secondary aim is to evaluate the strategy for the treatment of the complication, and if there is a correlation between morbidity/mortality and volume of the Bariatric Center

Details

Lead sponsorAzienda Sanitaria Locale Napoli 2 Nord
StatusENROLLING_BY_INVITATION
Enrolment10000
Start dateThu Jan 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionTue Jun 30 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

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