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NCT04642989
The Effect of Facial Effleurage on Acute Rhinosinusitis
NA trial testing Sham Treatment in Rhinosinusitis Acute in 138 participants. Completed in 1 September 2020.
1 September 2020
Quick facts
| Lead sponsor | Edward Via Virginia College of Osteopathic Medicine |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 138 |
| Start date | 1 September 2018 |
| Primary completion | 1 September 2020 |
| Estimated completion | 1 September 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Sham Treatment — full drug profile →
- Facial Effleurage
- Antibiotics — full drug profile →
Conditions studied
- Rhinosinusitis Acute — all drugs for Rhinosinusitis Acute →
Sponsor
Edward Via Virginia College of Osteopathic Medicine
Who can join
Adults 18 to 69, any sex, with Rhinosinusitis Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Rhinosinusitis accounts for 12% of the total antibiotic prescriptions filled in the United States annually; however, the majority of rhinosinusitis cases have been proposed to have a viral etiology, or are capable of spontaneously resolving. This overuse of antibiotics is contributing to the development of antibiotic-resistant human pathogenic bacteria, and increasing patient mortality to previously easily cured diseases. This is also causing an unnecessary financial burden especially for uninsured, rural families. Facial Effleurage (FE) is an osteopathic manipulative therapy that allows physicians an alternative therapy to prescribing antibiotics; however, the only scientific literature on the technique is weak in design and execution. This will be a randomized, placebo-controlled clinical trial to test the ability of FE to reduce symptom severity over time, reduce the cellular infiltrate into the nasal cavity, and to more quickly resolve the symptoms of rhinosinusitis compared to antibiotic treatment. This methodical approach to the efficacy of FE has the potential to impact the treatment recommendations of physicians immediately, and to convince more physicians to prescribe less antibiotics and rely more heavily on FE.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04642989
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Rhinosinusitis Acute
Currently open trials in the same condition.
- NCT06901297 — The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult Patients · Phase 3 · recruiting
Other Edward Via Virginia College of Osteopathic Medicine trials
Trials by the same sponsor.
- NCT06841627 — Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study · NA · completed
- NCT06858592 — Osteopathic Manipulative Techniques in Collegiate Dancers · NA · completed
- NCT06533345 — VCOM Pain Free Research Collaborative · NA · recruiting
- NCT06529991 — Self-Myofascial Release of the Upper Cervical Muscles · NA · recruiting
- NCT06471426 — The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04642989 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Edward Via Virginia College of Osteopathic Medicine
- Last refreshed: 24 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04642989.
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