NCT04640090 is a NA clinical trial of Smartphone app (Wysa) in Musculoskeletal Diseases, sponsored by Washington University School of Medicine.

Who is sponsoring NCT04640090?

NCT04640090 is sponsored by Washington University School of Medicine.

What drugs are being tested in NCT04640090?

Interventions in NCT04640090: Smartphone app (Wysa).

What condition does NCT04640090 study?

NCT04640090 studies Musculoskeletal Diseases, Chronic Pain, Anxiety Disorders, Depression.

Is NCT04640090 still recruiting?

NCT04640090 is currently completed. Last updated 1 December 2021.

Last reviewed 2021-12-01 · How we verify

NCT04640090

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Wellness Through Mobile Health

Completed NA Last updated 1 December 2021

What this trial tests

NA trial testing Smartphone app (Wysa) in Musculoskeletal Diseases in 60 participants. Completed in 14 September 2021.

Timeline

12 August 2020

Primary endpoint
14 September 2021

14 September 2021

Quick facts

Lead sponsor	Washington University School of Medicine
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	12 August 2020
Primary completion	14 September 2021
Estimated completion	14 September 2021
Sites	1 location across United States

Drugs / interventions tested

Smartphone app (Wysa)

Conditions studied

Musculoskeletal Diseases — all drugs for Musculoskeletal Diseases →
Chronic Pain — all drugs for Chronic Pain →
Anxiety Disorders — all drugs for Anxiety Disorders →
Depression — all drugs for Depression →

Sponsor

Washington University School of Medicine

Who can join

18 and older, any sex, with Musculoskeletal Diseases or Chronic Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This pilot project will evaluate the potential of an affordable smartphone app to improve users' mental well-being.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

A Digital Mental Health Intervention in an Orthopedic Setting for Patients With Symptoms of Depression and/or Anxiety: Feasibility Prospective Cohort Study.
Leo AJ, Schuelke MJ, Hunt DM, Metzler JP, et al · · 2022 · cited 37× · PMID 35039278 · DOI 10.2196/34889
Digital Mental Health Intervention Plus Usual Care Compared With Usual Care Only and Usual Care Plus In-Person Psychological Counseling for Orthopedic Patients With Symptoms of Depression or Anxiety: Cohort Study.
Leo AJ, Schuelke MJ, Hunt DM, Miller JP, et al · · 2022 · cited 23× · PMID 35507387 · DOI 10.2196/36203
Adherence and Engagement With a Cognitive Behavioral Therapy-Based Conversational Agent (Wysa for Chronic Pain) Among Adults With Chronic Pain: Survival Analysis.
Sinha C, Cheng AL, Kadaba M. · · 2022 · cited 15× · PMID 35526201 · DOI 10.2196/37302

Verify or expand the search:

Other recruiting trials for Musculoskeletal Diseases

Currently open trials in the same condition.

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NCT07004478 — Turkish Adaptation Study of the Generic Functional Index · recruiting
NCT06461000 — EULAR Impact of Rheumatic and Musculoskeletal Diseases Survey · recruiting
NCT07088965 — Musculoskeletal Disorders of Postgraduate Dentistry Students and Specialist Dentists · recruiting
NCT06175871 — New Clinical Rehabilitation Approach for the Management of Falls Risks · NA · recruiting

Other Washington University School of Medicine trials

Trials by the same sponsor.

NCT05521997 — Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer · Phase 2 · not yet recruiting
NCT07101666 — Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Phase 2 · not yet recruiting
NCT07200089 — Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel) · Phase 1 · not yet recruiting
NCT07313592 — Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients · not yet recruiting
NCT07419464 — 5-Fluorouracil Response and Optimization STudy (The FROST Trial) · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04640090 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Washington University School of Medicine
Last refreshed: 1 December 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04640090.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing