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NCT04639856
ICU Stay in Patients With Low Ejection Fraction Undergoing Cardiac Revascularization: Comparison of On-pump vs Off-pump Coronary Artery Bypass Grafting
NA trial testing Coronary Artery Bypass Grafting in Cardiac Revascularization in 60 participants. Completed in 15 January 2019.
15 January 2019
Quick facts
| Lead sponsor | Armed Forces Institute of Cardiology, Pakistan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 15 July 2018 |
| Primary completion | 15 January 2019 |
| Estimated completion | 15 January 2019 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Coronary Artery Bypass Grafting
Conditions studied
- Cardiac Revascularization — all drugs for Cardiac Revascularization →
Sponsor
Armed Forces Institute of Cardiology, Pakistan
Who can join
Adults 40 to 80, any sex, with Cardiac Revascularization. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Coronary artery bypass graft (CABG) surgery can result in severe postoperative complications, such as renal and pulmonary failure. In about 80% of the cases worldwide, it is currently performed with cardiopulmonary bypass (CPB) with cardiac arrest. Cardiopulmonary bypass leads to a systemic inflammatory response, which may be induced by the contact of circulating blood with artificial surfaces of the extracorporeal circuit.\[1\] To reduce postoperative complications caused by systemic inflammation, off-pump CABG was reintroduced into clinical practice in the early 1990s. During off-pump surgery, the coronary artery grafts are placed on coronaries of a beating heart, thereby avoiding aortic cross clamping and CPB. \[1\] There are many studies and debates about the two approaches to cardiac revascularization via CABG. This study aims to answer the question as to difference in the ICU stay of patients with low ejection fraction undergoing cardiac revascularization bet ween off pump and on pump coronary artery bypass grafting and better treatment option shall be adopted in future.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04639856
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Related trials
Other trials of Coronary Artery Bypass Grafting
Trials testing the same drug.
- NCT07373678 — CABG Versus PCI in Patients With Isolated LAD Chronic Total Occlusion · completed
- NCT03774342 — The Influence of Cognitive Decline on Quality of Life After Coronary Bypass · unknown
- NCT07362108 — Cardiovascular Events Related to Treated Coronary Arteries in Stable Multivessel CAD · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04639856 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Armed Forces Institute of Cardiology, Pakistan
- Last refreshed: 23 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04639856.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing