Last reviewed · How we verify
NCT04638777: rTMS-PD
Repetitive Transcranial Magnetic Stimulation With H-coil in Parkinson's Disease (rTMS-PD)
NA trial testing rTMS with H-coil in Parkinson Disease in 60 participants. Completed in 2 July 2012.
8 June 2012
Quick facts
| Lead sponsor | Giancarlo Comi |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 27 September 2010 |
| Primary completion | 8 June 2012 |
| Estimated completion | 2 July 2012 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- rTMS with H-coil
- rTMS with H-coil
- rTMS with H-coil
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
Giancarlo Comi
Who can join
Under 80, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Focal repetitive transcranial magnetic stimulation (rTMS) has been applied to improve symptoms in Parkinson disease (PD) with conflicting results. However, the stimulation with H-coil has been shown to stimulate a wider cortical area compared with the standard coils, with preliminary results confirming the potential efficacy of the treatment. In this study the investigators aimed to explore the safety and efficacy of excitatory rTMS with H-coil on PD motor symptoms.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Bilateral Repetitive Transcranial Magnetic Stimulation With the H-Coil in Parkinson's Disease: A Randomized, Sham-Controlled Study.
Spagnolo F, Fichera M, Chieffo R, Dalla Costa G, et al · · 2020 · cited 24× · PMID 33679570 · DOI 10.3389/fneur.2020.584713
Verify or expand the search:
- PubMed search for NCT04638777
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of rTMS with H-coil
Trials testing the same drug.
- NCT04562506 — Repetitive Transcranial Magnetic Stimulation With H-coil in Alzheimer's Disease · NA · completed
Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
- NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
- NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
- NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
- NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
- NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting
Other Giancarlo Comi trials
Trials by the same sponsor.
- NCT04562506 — Repetitive Transcranial Magnetic Stimulation With H-coil in Alzheimer's Disease · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04638777 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Giancarlo Comi
- Last refreshed: 20 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04638777.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing