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NCT04628377
Prognostic Implication of Angiography-Derived IMR in STEMI Patients
trial testing Angiography-drived Index of Microcirculatory Resistance in Acute ST-segment Elevation Myocardial Infarction in 333 participants. Completed in 1 April 2023.
1 March 2023
Quick facts
| Lead sponsor | Samsung Medical Center |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 333 |
| Start date | 26 May 2003 |
| Primary completion | 1 March 2023 |
| Estimated completion | 1 April 2023 |
Drugs / interventions tested
- Angiography-drived Index of Microcirculatory Resistance
Conditions studied
- Acute ST-segment Elevation Myocardial Infarction — all drugs for Acute ST-segment Elevation Myocardial Infarction →
Sponsor
Samsung Medical Center
Who can join
19 and older, any sex, with Acute ST-segment Elevation Myocardial Infarction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of STEMI patients. Previous study presented that index of microcirculatory resistance (IMR) in culprit vessel of STEMI patients showed significant association with the risk of cardiac death or heart failure admission. Recent technical development enabled angiographic derivation of IMR without pressure wire, hyperemic agents, or theromdilution method. In this regard, the current study will evaluate prognostic implication of angiography-derived IMR in STEMI patients who were successfully revascularized.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Functional Coronary Angiography-Derived Index of Microcirculatory Resistance in Patients With ST-Segment Elevation Myocardial Infarction.
Choi KH, Dai N, Li Y, Kim J, et al · · 2021 · cited 115× · PMID 34353599 · DOI 10.1016/j.jcin.2021.05.027
Verify or expand the search:
- PubMed search for NCT04628377
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Angiography-drived Index of Microcirculatory Resistance
Trials testing the same drug.
- NCT04825028 — Diagnostic and Prognostic Value of Angiography-derived IMR · unknown
Other Samsung Medical Center trials
Trials by the same sponsor.
- NCT07482865 — Routine Versus Provisional Distal Perfusion Catheter Placement in Patients Undergoing Mechanical Circulatory Support · NA · not yet recruiting
- NCT07467213 — Routine Use of Potassium Competitive Acid Blocker vs. Guideline-Directed Gastrointestinal Protection Strategy in Acute M · Phase 4 · not yet recruiting
- NCT07530913 — Effectiveness Analysis of a Rehabilitation Exercise Platform for Living Donor Liver Transplantation Patients · NA · enrolling by invitation
- NCT07500701 — Salvage Moderate Hypofractionated Versus Ultrahypofractionated Radiotherapy for Biochemical Recurrence After Radical Pro · Phase 3 · recruiting
- NCT07409441 — Korea Acute Myocardial Infarction Registry · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04628377 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Samsung Medical Center
- Last refreshed: 12 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04628377.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing