Who is sponsoring NCT04626817?

NCT04626817 is sponsored by Cevriye Mülkoğlu.

What drugs are being tested in NCT04626817?

Interventions in NCT04626817: Isokinetic device (Biodex System 4).

What condition does NCT04626817 study?

NCT04626817 studies Muscle Strength.

Is NCT04626817 still recruiting?

NCT04626817 is currently completed. Last updated 13 November 2020.

Last reviewed 2020-11-13 · How we verify

NCT04626817

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Oral Isotretinoin on Muscle Strength in Patients With Acne Vulgaris: A Prospective Controlled Study

Completed NA Last updated 13 November 2020

What this trial tests

NA trial testing Isokinetic device (Biodex System 4) in Muscle Strength in 60 participants. Completed in 1 October 2019.

Timeline

1 September 2018

Primary endpoint
1 October 2019

1 October 2019

Quick facts

Lead sponsor	Cevriye Mülkoğlu
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	screening
Enrollment	60
Start date	1 September 2018
Primary completion	1 October 2019
Estimated completion	1 October 2019
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Isokinetic device (Biodex System 4)

Conditions studied

Muscle Strength — all drugs for Muscle Strength →

Sponsor

Cevriye Mülkoğlu

Who can join

Adults 18 to 45, any sex, with Muscle Strength. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

BACKGROUND: Musculoskeletal side effects related to isotretinoin are frequently reported. This study aimed to investigate the effect of oral isotretinoin treatment on muscle strength. Our second aim was to evaluate whether there was a correlation between the serum creatine phosphokinase (CPK) level, a specific marker of muscle breakdown, and muscle strength. METHODS: This study included 30 patients who presented to our hospital and were started on oral isotretinoin treatment for acne vulgaris and 30 patients in the control group who were given local treatment. Age, gender, height and weight of the patients were recorded, and the body mass index (BMI) was calculated. The hamstring and quadriceps muscle strengths of the non-dominant side were evaluated in all patients using an isokinetic dynamometer, and the peak torque (PT) values were recorded. In the isotretinoin group, isokinetic measurements were performed again in those that completed six-month drug treatment and compared with the initial PT values.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of oral isotretinoin on muscle strength in patients with acne vulgaris: a prospective controlled study.
Mülkoğlu C, Karaosmanoğlu N. · · 2021 · cited 2× · PMID 33743831 · DOI 10.1186/s40360-021-00483-0

Verify or expand the search:

Other recruiting trials for Muscle Strength

Currently open trials in the same condition.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04626817 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cevriye Mülkoğlu
Last refreshed: 13 November 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04626817.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing