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NCT04625413: UR-GOAL 1

A Patient-centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists

Completed NA Results posted Last updated 22 January 2026
What this trial tests

NA trial testing Behavioral: UR-GOAL communication tool in Acute Myeloid Leukemia in 15 participants. Completed in 11 October 2022.

Timeline
23 October 2021
Primary endpoint
11 October 2022
11 October 2022

Quick facts

Lead sponsorUniversity of Rochester
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposesupportive care
Enrollment15
Start date23 October 2021
Primary completion11 October 2022
Estimated completion11 October 2022
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Rochester

Who can join

60 and older, any sex, with Acute Myeloid Leukemia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Feasibility (Recruitment Rates) Primary · Four weeks

Percentage of patients who consented to the study ultimately completed the study intervention and post-intervention assessment

GroupValue95% CI
Experimental: Experimental Arm: Single11
Usefulness Primary · Four weeks

Usefulness was assessed using the Preparation for Decision Making Scale (mean score range from 1 to 5, and higher scores indicate greater usefulness)

GroupValue95% CI
Experimental: Experimental Arm: Single3.8± 0.7
Pre-post Changes in the Following Outcomes:Perceived Efficacy in Patient-Physician Interactions (PEPPI) Secondary · Four weeks

A valid and reliable assessment of perceived self-efficacy of older patients interacting with physicians; score on 5-item scale, ranging 5-25; higher score corresponds to greater perceived efficacy. Pre-post changes from baseline to four weeks.

GroupValue95% CI
Experimental: Experimental Arm: Single1.5± 3.0
Pre-post Changes in the Following Outcomes: General Anxiety Disorder-7 Secondary · Four weeks

A 7-item screening tool for anxiety; ranging 7-21; higher score corresponds to greater anxiety symptoms. Pre-post changes from baseline to four weeks.

GroupValue95% CI
Experimental: Experimental Arm: Single-1.6± 5.4
Pre-post Changes in the Following Outcomes: Geriatric Depression Scale-15 Secondary · Four Weeks

A 15-item valid and reliable screening tool for depression in older adults. This will be used for patients; ranging 0-15; higher score corresponds to greater depressive symptoms. Pre-post changes from baseline to four weeks.

GroupValue95% CI
Experimental: Experimental Arm: Single0.2± 2.1

Sponsor's own description

This is a pilot study to evaluate the usability and feasibility of a patient-centered communication tool (University of Rochester-Geriatric Oncology Assessment for acute myeloid Leukemia or UR-GOAL) among 15 older patients with AML, their caregivers, and oncologists.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Aging and Age-Related Epigenetic Drift in the Pathogenesis of Leukemia and Lymphomas: New Therapeutic Targets.
    Allegra A, Caserta S, Mirabile G, Gangemi S. · · 2023 · cited 17× · PMID 37830606 · DOI 10.3390/cells12192392
  2. Adapting a patient-centered communication tool for older patients with acute myeloid leukemia and their oncologist.
    Watson E, Sanapala C, Cortes AM, Klepin HD, et al · · 2022 · cited 8× · PMID 35930701 · DOI 10.1182/bloodadvances.2022008041
  3. Patient-oncologist discussion of treatment decisions: Exploring the role of a patient-centered communication tool for older adults with acute myeloid leukemia and their caregivers.
    Jensen-Battaglia M, LoCastro M, Oh H, Sanapala C, et al · · 2024 · cited 1× · PMID 38336521 · DOI 10.1016/j.jgo.2024.101716
  4. In-person and virtual assessment of short physical performance battery test in older adults with myeloid malignancies.
    Sanapala C, Jensen-Battaglia M, Watson EE, Konatham S, et al · · 2023 · cited 1× · PMID 36790922 · DOI 10.1182/bloodadvances.2022009396

Verify or expand the search:

Other recruiting trials for Acute Myeloid Leukemia

Currently open trials in the same condition.

Other University of Rochester trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04625413.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing