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NCT04619667
Effects of a New Interface for NIV on Respiratory Drive
NA trial testing High Flow Nasal Cannula (HFNC) in Acute Respiratory Failure in 22 participants. Status unknown.
31 December 2021
Quick facts
| Lead sponsor | University Magna Graecia |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 1 December 2020 |
| Primary completion | 31 December 2021 |
| Estimated completion | 31 December 2021 |
Drugs / interventions tested
- High Flow Nasal Cannula (HFNC)
- Continuous Positive Airway Pressure (CPAP)
Conditions studied
- Acute Respiratory Failure — all drugs for Acute Respiratory Failure →
Sponsor
University Magna Graecia
Who can join
18 and older, any sex, with Acute Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This pilot physiologic randomized cross-over study was designed to investigate if, in patients with hARF, a new device combining high-flow oxygen through nasal cannula (HFNC) and continuous positive airway pressure (CPAP) reduces the respiratory effort, as compared to HFNC and CPAP alone (first outcome). Furthermore, the diaphragm activation, as assessed with ultrasound, gas exchange and patient's comfort among different settings will be assessed (secondary outcomes).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04619667
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High Flow Nasal Cannula (HFNC)
Trials testing the same drug.
- NCT05475119 — Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea · NA · unknown
- NCT04619641 — Physiological Effects of a New Interface on Lung Ventilation and Gas Distribution · NA · unknown
- NCT03615417 — High-Flow Nasal Cannula (HFNC) Preoxygenation in Obese Patients Undergoing General Anesthesia · NA · completed
Other recruiting trials for Acute Respiratory Failure
Currently open trials in the same condition.
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- NCT06912360 — Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso · NA · recruiting
- NCT06876168 — Virtual Reality in ICU - PARTNER · recruiting
- NCT06952816 — Validation Study of the EMILY AI Device in Acute and Chronic Respiratory Failure · NA · recruiting
- NCT06934876 — Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adul · recruiting
Other University Magna Graecia trials
Trials by the same sponsor.
- NCT07173660 — Consensus Statements on Deep Brain Stimulation in Patients With Parkinson's Disease · not yet recruiting
- NCT06830460 — Measurement of the Optic Nerve Diameter in Different Healthcare Operators · NA · not yet recruiting
- NCT06274931 — Analysis of the Pulmonary Microbiome · unknown
- NCT05398289 — FOUR-SIX TRIAL for the Treatment of Enterococcal Endocarditis · Phase 4 · not yet recruiting
- NCT05681962 — Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04619667 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Magna Graecia
- Last refreshed: 16 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04619667.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing