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NCT04617652
Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation
Phase 4 trial testing Magnesium sulfate in Smooth Extubation in 60 participants. Completed in 1 April 2021.
1 February 2021
Quick facts
| Lead sponsor | Fayoum University Hospital |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 60 |
| Start date | 1 August 2020 |
| Primary completion | 1 February 2021 |
| Estimated completion | 1 April 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Magnesium sulfate — full drug profile →
- Normal saline
Conditions studied
- Smooth Extubation — all drugs for Smooth Extubation →
Sponsor
Fayoum University Hospital
Who can join
Adults 18 to 65, any sex, with Smooth Extubation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Tracheal extubation is a critical event in the anaesthetic management of patients undergoing general anaesthesia with endotracheal intubation for elective procedures. It the state of art to provide suitable conditions for smooth extubation and avoid coughing, bucking, straining and/or laryngospasm. Several methods have been described to provide a smooth extubation, including the use of remifentanil infusion, dexmedetomidine or fentanyl. Because of its anti-inflammatory and analgesic effects and lack of respiratory depressant actions, magnesium sulphate could be an attractive alternative.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04617652
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Magnesium sulfate
Trials testing the same drug.
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- NCT07213037 — Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sin · Phase 3 · not yet recruiting
- NCT06979141 — Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia · Phase 3 · recruiting
- NCT07131033 — Esketamine Combined With Magnesium Sulfate for Postoperative Fatigue Syndrome in Patients Undergoing Laparoscopic Cholec · Phase 1, PHASE2 · active not recruiting
Other Fayoum University Hospital trials
Trials by the same sponsor.
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- NCT07187310 — EXORA vs ESP Blocks in Laparoscopic Cholecystectomy · NA · recruiting
- NCT07205757 — Adding Lidocaine to Custodiol Mixture · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04617652 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fayoum University Hospital
- Last refreshed: 19 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04617652.
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