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NCT04614051

Safety Evaluation of Autologous Dendritic Cell Anticancer Immune Cell Therapy (Cellgram-DC)

Terminated Phase 1 Last updated 3 January 2023
What this trial tests

Phase 1 trial testing Cellgram-DC in Ovarian Cancer in 2 participants. Terminated before completion.

Timeline
30 March 2021
Primary endpoint
10 May 2022
10 May 2022

Quick facts

Lead sponsorPharmicell Co., Ltd.
PhasePhase 1
StatusTerminated
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment2
Start date30 March 2021
Primary completion10 May 2022
Estimated completion10 May 2022
Sites1 location across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Pharmicell Co., Ltd. — full company profile →

Who can join

Adults 19 to 79, female only, with Ovarian Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This Phase 1 study to evaluate the safety of cancer immunotherapy with autologous dendritic cells in patients with advanced or recurrent epithelial ovarian cancer

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Trial watch: Dendritic cell (DC)-based immunotherapy for cancer.
    Laureano RS, Sprooten J, Vanmeerbeerk I, Borras DM, et al · · 2022 · cited 101× · PMID 35800158 · DOI 10.1080/2162402x.2022.2096363
  2. Dendritic Cell Vaccines: A Promising Approach in the Fight against Ovarian Cancer.
    Caro AA, Deschoemaeker S, Allonsius L, Coosemans A, et al · · 2022 · cited 22× · PMID 36011029 · DOI 10.3390/cancers14164037
  3. Trial watch: anticancer vaccination with dendritic cells.
    Borges F, Laureano RS, Vanmeerbeek I, Sprooten J, et al · · 2024 · cited 18× · PMID 39398476 · DOI 10.1080/2162402x.2024.2412876
  4. Integrating Cancer Vaccines in the Standard-of-Care of Ovarian Cancer: Translating Preclinical Models to Human.
    Chiang CL, Rovelli R, Sarivalasis A, Kandalaft LE. · · 2021 · cited 8× · PMID 34572778 · DOI 10.3390/cancers13184553
  5. Application of dendritic cell extracellular vesicles as a valid nanoparticle platform for cancer therapies: a narrative review.
    Nezamdoust FV, Nezhad-Mokhtari P, Mirzaahmadi B, Mazloumi Z, et al · · 2026 · PMID 42010708 · DOI 10.1186/s13287-026-05011-7

Verify or expand the search:

Other recruiting trials for Ovarian Cancer

Currently open trials in the same condition.

Other Pharmicell Co., Ltd. trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04614051.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing