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The Effect of Esketamine on Patients Undergoing Tumor Surgery
Although the acute and chronic postoperative pain of surgical patients has gradually been paid attention to, it has not yet been better resolved.and, the incidence of anxiety and depression in cancer patients is constantly increasing，The new analgesic anesthetic esketamine hydrochloride was launched in China last year，however, in the domestic and foreign literature, there are still few reports of esketamine hydrochloride in postoperative analgesia, and most of them are retrospective and small samples.This study aims to investigate whether esketamine has advantages over traditional opioids in terms of postoperative analgesia, anxiety and depression in cancer patients.
Details
| Lead sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 282 |
| Start date | Sat Aug 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Fri Oct 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Tumor Surgery
Interventions
- High-dose Esketamine hydrochloride+Hydromorphone
- Low-dose Esketamine hydrochloride+Hydromorphone
- Hydromorphone
Countries
China