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NCT04613297: HLA-G-COVID

HLA-G Immuno-Inhibitor Checkpoint Study in Patients With COVID-19 Infection: Molecular and Cellular Assessment

Completed NA Last updated 3 August 2022
What this trial tests

NA trial testing Baseline and during hospitalization blood samples in Covid19 in 91 participants. Completed in 19 July 2022.

Timeline
19 October 2020
Primary endpoint
19 July 2022
19 July 2022

Quick facts

Lead sponsorHopital Foch
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposeother
Enrollment91
Start date19 October 2020
Primary completion19 July 2022
Estimated completion19 July 2022
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Hopital Foch — full company profile →

Who can join

18 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the research is to study the immune checkpoint linked to the HLA-G molecule in the dysregulation of the control of COVID-19 infection.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Perspective of HLA-G Induced Immunosuppression in SARS-CoV-2 Infection.
    Lin A, Yan WH. · · 2021 · cited 22× · PMID 34938296 · DOI 10.3389/fimmu.2021.788769
  2. Association of <i>HLA-G</i> 3'UTR Polymorphisms with Response to First-Line FOLFIRI Treatment in Metastatic Colorectal Cancer.
    Scarabel L, Polesel J, De Mattia E, Buonadonna A, et al · · 2022 · cited 6× · PMID 36559230 · DOI 10.3390/pharmaceutics14122737

Verify or expand the search:

Other recruiting trials for Covid19

Currently open trials in the same condition.

Other Hopital Foch trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04613297.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing