NCT04610944 is a NA clinical trial of Changing Talk Online (CHATO) in Dementia, sponsored by University of Kansas Medical Center.

Who is sponsoring NCT04610944?

NCT04610944 is sponsored by University of Kansas Medical Center.

What drugs are being tested in NCT04610944?

Interventions in NCT04610944: Changing Talk Online (CHATO).

What condition does NCT04610944 study?

NCT04610944 studies Dementia, Alzheimer Disease, Communication.

Is NCT04610944 still recruiting?

NCT04610944 is currently active, enrolled. Last updated 14 April 2026.

Last reviewed 2026-04-14 · How we verify

NCT04610944

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Changing Talk Online Training (CHATO) National Trial

Active, enrolled NA Last updated 14 April 2026

What this trial tests

NA trial testing Changing Talk Online (CHATO) in Dementia in 5,043 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

26 April 2021

Primary endpoint
30 April 2026

31 May 2026

Quick facts

Lead sponsor	University of Kansas Medical Center
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	supportive care
Enrollment	5,043
Start date	26 April 2021
Primary completion	30 April 2026
Estimated completion	31 May 2026
Sites	1 location across United States

Drugs / interventions tested

Changing Talk Online (CHATO)

Conditions studied

Dementia — all drugs for Dementia →
Alzheimer Disease — all drugs for Alzheimer Disease →
Communication — all drugs for Communication →

Sponsor

University of Kansas Medical Center

Who can join

18 and older, any sex, with Dementia or Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The National Plan to Address Alzheimer's disease has identified education of dementia care providers as a top priority to address the need for quality care for the population of persons with dementia that will triple in the next 30 years. This study will test new online interactive training for nursing home staff that improves staff communication and also reduces behavioral symptoms of persons with dementia that they care for. Innovative approaches to reach care providers are essential to achieve implementation of evidence-based practices to improve care.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Promoting Elderspeak Awareness: Adapting Changing Talk Online Communication Education for Adult Day Services Staff.
Williams K, Coleman CK, Hein M, Shaw C, et al · · 2023 · cited 7× · PMID 36944174 · DOI 10.3928/19404921-20230220-04
Changing Talk Online: Protocol for a cluster pragmatic trial testing communication education to reduce behavioral and psychological symptoms of dementia in nursing home care.
Williams KN, Coleman CK, Shaw CA, Perkhounkova Y, et al · · 2021 · cited 2× · PMID 34478869 · DOI 10.1016/j.cct.2021.106550

Verify or expand the search:

Other trials of Changing Talk Online (CHATO)

Trials testing the same drug.

NCT03849937 — Changing Talk Online (CHATO) Study · NA · completed

Other recruiting trials for Dementia

Currently open trials in the same condition.

NCT07531589 — BrainLive Connect: Non-professional Delivered CST for People Living With Dementia · NA · recruiting
NCT07290387 — Tele-Savvy for Latino Caregivers · NA · recruiting
NCT06088810 — The Impact of Music Intervention on Sleep · NA · recruiting
NCT07482800 — Dementia in Fiction and Clinical Narratives · recruiting
NCT07392944 — Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Home · NA · recruiting

Other University of Kansas Medical Center trials

Trials by the same sponsor.

NCT06636214 — Adapting Changing Talk: Online (CHATO) to CHATO-Inclusive · NA · not yet recruiting
NCT07528963 — KanSurvive 2.0: Testing Enhanced Models of Cancer Survivorship Care for Rural Cancer Survivors in Primary Care Practice · NA · enrolling by invitation
NCT07463755 — Low-Fidelity Driving Simulator Training in Parkinson's Disease. · NA · not yet recruiting
NCT07420621 — Preliminary Effectiveness of Enhanced Text Message + Incentives · NA · recruiting
NCT07491510 — Improving Prenatal Care to Reduce Early Onset Preeclampsia in Low-Income · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04610944 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Kansas Medical Center
Last refreshed: 14 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04610944.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing