NCT04610710 (EFFORT) is a NA clinical trial of Operation in Deep Endometriosis, sponsored by Horsens Hospital.

Who is sponsoring NCT04610710?

NCT04610710 is sponsored by Horsens Hospital.

What drugs are being tested in NCT04610710?

Interventions in NCT04610710: Operation, Fertility treatment.

What condition does NCT04610710 study?

NCT04610710 studies Deep Endometriosis, Infertility, Female.

Is NCT04610710 still recruiting?

NCT04610710 is currently terminated. Last updated 10 March 2026.

Last reviewed 2026-03-10 · How we verify

NCT04610710: EFFORT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Operation on Fertility for Women With Severe Endometriosis

Terminated NA Last updated 10 March 2026

What this trial tests

NA trial testing Operation in Deep Endometriosis in 38 participants. Terminated before completion.

Timeline

25 November 2020

Primary endpoint
1 March 2026

1 March 2026

Quick facts

Lead sponsor	Horsens Hospital
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	38
Start date	25 November 2020
Primary completion	1 March 2026
Estimated completion	1 March 2026
Sites	3 locations across Denmark, France

Drugs / interventions tested

Operation
Fertility treatment

Conditions studied

Deep Endometriosis — all drugs for Deep Endometriosis →
Infertility, Female — all drugs for Infertility, Female →

Sponsor

Horsens Hospital

Who can join

Adults 18 to 38, female only, with Deep Endometriosis or Infertility, Female. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The EFFORT study compares the impact on fertility of operation or fertility treatment (IVF, in vitro fertilization) in a multicenter randomized controlled trial. The study population consists of women with colorectal deep infiltrating endometriosis and a pregnancy intention. These women will be randomized to either of the two treatment groups: Group A = Operation or Group B = fertility treatment (IVF). Group A will be further divided postoperatively into spontaneous conception or IVF depending on the Endometriosis Fertility Index score.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Deep Endometriosis and Infertility: What Is the Impact of Surgery?
Daniilidis A, Angioni S, Di Michele S, Dinas K, et al · · 2022 · cited 24× · PMID 36431203 · DOI 10.3390/jcm11226727
EFFORT study: Comparing impact of operation and assisted reproductive technologies on fertility for women with deep infiltrating endometriosis - study protocol for a multicentre randomised trial.
Raos M, Roman H, Seyer-Hansen M, Kesmodel US, et al · · 2022 · cited 5× · PMID 35410921 · DOI 10.1136/bmjopen-2021-052877
The (cost-) effectiveness Of Surgical excision of Colorectal endometriosis compared to ART treatment trAjectory (TOSCA study) - a study protocol.
de Koning R, Cantineau AEP, van der Tuuk K, De Bie B, et al · · 2024 · cited 3× · PMID 38583465 · DOI 10.1530/raf-23-0048

Verify or expand the search:

Other trials of Operation

Trials testing the same drug.

NCT05555459 — Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation · NA · recruiting
NCT04573387 — Exhaustive Drainage Versus Fixed-time Drainage for Chronic Subdural Hematoma After One-burr Hole Craniostomy · NA · completed
NCT03067454 — Early Mobilization of Spiral Metacarpal Fractures Compared With Operative Treatment · NA · completed

Other recruiting trials for Deep Endometriosis

Currently open trials in the same condition.

NCT06386276 — Surgical TReatment of Women With Deep ENDometriosis · recruiting
NCT05179109 — Robotic Versus Laparoscopic Surgery for Deep Endometriosis · NA · recruiting
NCT06799767 — Radiological Diagnostics in Patients With Deep Endometriosis · recruiting

Other Horsens Hospital trials

Trials by the same sponsor.

NCT07105657 — The Outcome of Three Weeks Rehabilitation in Patients With a Total Hip or Knee Replacement Experiencing Persistent Physi · recruiting
NCT05031390 — the Horsens Aarhus FemoroAcetabular Impingement Syndrome Training Pilot Study · NA · completed
NCT04590924 — HAFAI Cohort 5 Year Follow up of Patients With Femoroacetabular Impingement Undergoing Hip Arthroscopy · completed
NCT03868826 — Pain, Function and Quality of Life Before and After Treatment of Hamstring Avulsion · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04610710 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Horsens Hospital
Last refreshed: 10 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04610710.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing