NCT04605458 is a NA clinical trial of Contingency Management in Smoking Cessation, sponsored by Medical University of South Carolina.

Who is sponsoring NCT04605458?

NCT04605458 is sponsored by Medical University of South Carolina.

What drugs are being tested in NCT04605458?

Interventions in NCT04605458: Contingency Management, Standard Care.

What condition does NCT04605458 study?

NCT04605458 studies Smoking Cessation.

Is NCT04605458 still recruiting?

NCT04605458 is currently completed. Last updated 5 March 2026.

Last reviewed 2026-03-05 · How we verify

NCT04605458

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Contingency Management to Promote Smoking Abstinence in Cancer Patients

Completed NA Last updated 5 March 2026

What this trial tests

NA trial testing Contingency Management in Smoking Cessation in 282 participants. Completed in 18 December 2025.

Timeline

25 November 2020

Primary endpoint
10 July 2025

18 December 2025

Quick facts

Lead sponsor	Medical University of South Carolina
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	282
Start date	25 November 2020
Primary completion	10 July 2025
Estimated completion	18 December 2025
Sites	1 location across United States

Drugs / interventions tested

Contingency Management
Standard Care — full drug profile →

Conditions studied

Smoking Cessation — all drugs for Smoking Cessation →

Sponsor

Medical University of South Carolina

Who can join

18 and older, any sex, with Smoking Cessation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a smoking cessation treatment study. Patients who have a cancer or a suspected cancer who will undergo surgical removal of their cancer are eligible to participate in this study. A novel smoking cessation treatment will be provided to half of the participants in the study. All study participants will receive standard smoking cessation therapy including counseling and the nicotine patch.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Incentives for smoking cessation.
Notley C, Gentry S, Livingstone-Banks J, Bauld L, et al · · 2025 · cited 9× · PMID 39799985 · DOI 10.1002/14651858.cd004307.pub7
Preoperative contingency management intervention for smoking abstinence in cancer patients: trial protocol for a multisite randomised controlled trial.
Rojewski AM, Fucito LM, Baker NL, Palmer AM, et al · · 2021 · cited 1× · PMID 34187835 · DOI 10.1136/bmjopen-2021-051226

Verify or expand the search:

Other trials of Contingency Management

Trials testing the same drug.

NCT07281378 — Reducing Co-occurring Substance Use and HIV Risk Among Stimulant-using Men at High Risk for HIV in the United States of · NA · not yet recruiting
NCT07218471 — Cannabis Reduction and Functional Outcomes · NA · recruiting
NCT07226596 — Non-Abstinence Outcomes in Methamphetamine Use Disorder · NA · recruiting
NCT07129902 — Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department · NA · not yet recruiting
NCT06432985 — Smoking Cessation CM for Veterans With or at Risk for Cancer · NA · recruiting

Other recruiting trials for Smoking Cessation

Currently open trials in the same condition.

NCT07420621 — Preliminary Effectiveness of Enhanced Text Message + Incentives · NA · recruiting
NCT07224087 — Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients · Phase 1 · recruiting
NCT07331519 — Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer · NA · recruiting
NCT07210567 — Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors · NA · recruiting
NCT07129590 — Trauma-Informed Care for Smoking Cessation for Pregnancy · NA · recruiting

Other Medical University of South Carolina trials

Trials by the same sponsor.

NCT06491264 — Multiparameter Optimized tES for Memory in Aging · NA · withdrawn
NCT07513389 — Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) · Phase 2 · not yet recruiting
NCT03101917 — Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE) · NA · not yet recruiting
NCT07149207 — Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors · Phase 2 · recruiting
NCT06148038 — CBD for Breast Cancer Primary Tumors · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04605458 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of South Carolina
Last refreshed: 5 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04605458.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing