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NCT04604366
Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage
Phase 2 trial testing misoprostol in Miscarriage in 120 participants. Completed in 31 December 2021.
15 December 2021
Quick facts
| Lead sponsor | Islamabad Medical and Dental College |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 2 November 2020 |
| Primary completion | 15 December 2021 |
| Estimated completion | 31 December 2021 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- misoprostol (Misoprostol) — full drug profile →
Conditions studied
- Miscarriage — all drugs for Miscarriage →
- Misoprostol — all drugs for Misoprostol →
Sponsor
Islamabad Medical and Dental College
Who can join
Adults 20 to 40, female only, with Miscarriage or Misoprostol. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The miscarriage is one of the adverse outcomes of pregnancy and is responsible for stress and anxiety of the couple. there are different types of miscarriages.missed miscarriage also known as early fetal demise is one of the type of miscarriage in which patient is mostly asymptomatic but Ultrasound shows absent fetal cardiac activity.Traditionally surgical evacuation of uterus was the treatment of choice for miscarriage.The treatment of miscarriage has evolved significantly in recent years.medical management using misoprostol is the newest treatment option.Misoprostol is a synthetic prostaglandin E(1) analogue that is commonly used for medical miscarriage It can be given orally, vaginally and sublingually.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04604366
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other trials of misoprostol
Trials testing the same drug.
- NCT05077540 — Oxytocin Versus, Sublingual Misoprostol in the Secondary Prevention of Postpartum Hemorrhage After Vaginal Delivery · NA · unknown
- NCT04505943 — Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device Insertion · NA · unknown
- NCT04505917 — Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women · NA · unknown
- NCT03870256 — Oral Tranexamic Acid Plus Sublingual Misoprostol in Atonic Postpartum Hemorrhage · NA · completed
- NCT03710317 — Carbetocin Versus Buccal Misoprostol Plus IV Tranexamic Acid for Prevention of Postpartum Hemorrhage at Cesarean Section · NA · completed
Other recruiting trials for Miscarriage
Currently open trials in the same condition.
- NCT07109947 — Use of Aromatase Inhibitor Before Misoprostol in Medical Termination of Miscarriage · NA · recruiting
- NCT06576622 — PERIodontal Disease, Microbiota and Miscarriage · recruiting
- NCT06862089 — A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV · recruiting
- NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
- NCT05725512 — Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages · Phase 4 · recruiting
Other Islamabad Medical and Dental College trials
Trials by the same sponsor.
- NCT07532044 — Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation · NA · not yet recruiting
- NCT07257874 — Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy · Phase 3 · active not recruiting
- NCT07380841 — Metformin vs Inositol vs Diet vs Combination Therapy in PCOS · NA · completed
- NCT06243601 — Effect of Aloe Vera Gel as an Intra Canal Medicament · NA · completed
- NCT06125873 — Effect of Moringa Leaf Capsules on Glycemic Control of Type 2 Diabetic Patients · Phase 2 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04604366 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Islamabad Medical and Dental College
- Last refreshed: 24 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04604366.
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