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NCT04602260
Functional Recovery of Hospitalised Patients With COVID-19: The COREG Extension Study
trial in Covid19 in 211 participants. Completed in 31 March 2024.
8 January 2024
Quick facts
| Lead sponsor | McMaster University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 211 |
| Start date | 9 June 2020 |
| Primary completion | 8 January 2024 |
| Estimated completion | 31 March 2024 |
| Sites | 1 location across Canada |
Conditions studied
- Covid19 — all drugs for Covid19 →
- Corona Virus Infection — all drugs for Corona Virus Infection →
- Mobility Limitation — all drugs for Mobility Limitation →
- Frailty — all drugs for Frailty →
Sponsor
McMaster University
Who can join
18 and older, any sex, with Covid19 or Corona Virus Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Older adults and those with chronic underlying health conditions are the most susceptible to COVID-19 and its complications. Although there has been a rapid response to studying the effects of COVID-19 in the acute stages, little is known about recovery over the longer-term. Older adults who survive the diseases are at risk of developing persistent mobility limitations due to extensive bed rest during hospitalization. For older patients and those with underlying frailty recovering from COVID-19, this could rapidly lead to significant physical deconditioning and rapid declines in mobility. Understanding the trajectory of functional recovery of older hospitalised patients with COVID-19 in the short- and long-term is critical to improving patient outcomes and informing health and rehabilitative interventions for survivors.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Post-acute COVID-19 syndrome.
Nalbandian A, Sehgal K, Gupta A, Madhavan MV, et al · · 2021 · cited 3355× · PMID 33753937 · DOI 10.1038/s41591-021-01283-z -
Functional recovery following hospitalisation of patients diagnosed with COVID-19: a protocol for a longitudinal cohort study.
Reid JC, Costa AP, Duong M, Ho T, et al · · 2021 · cited 4× · PMID 34903545 · DOI 10.1136/bmjopen-2021-053021 -
Functional recovery 2-years after hospitalization for COVID-19: Insights from the COREG-FR extension study.
Beauchamp M, Farley C, Kirkwood R, Jones A, et al · · 2025 · PMID 41071807 · DOI 10.1371/journal.pone.0334212
Verify or expand the search:
- PubMed search for NCT04602260
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other McMaster University trials
Trials by the same sponsor.
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- NCT07408128 — Partner4Exercise Randomized Controlled Trial · Phase 2, PHASE3 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04602260 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by McMaster University
- Last refreshed: 25 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04602260.
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