NCT04599595 is a clinical trial of Peristeen (Coloplast) in Multiple Sclerosis, sponsored by University Hospital of Ferrara.

Who is sponsoring NCT04599595?

NCT04599595 is sponsored by University Hospital of Ferrara.

What drugs are being tested in NCT04599595?

Interventions in NCT04599595: Peristeen (Coloplast).

What condition does NCT04599595 study?

NCT04599595 studies Multiple Sclerosis, Intestinal Dysfunction, Anal Incontinence, Microbiota.

Is NCT04599595 still recruiting?

NCT04599595 is currently completed. Last updated 22 October 2020.

Last reviewed 2020-10-22 · How we verify

NCT04599595

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Characteristics of INTESTINAL DYSFUNCTION in Patients With MULTIPLE SCLEROSIS

Completed Last updated 22 October 2020

What this trial tests

trial testing Peristeen (Coloplast) in Multiple Sclerosis in 100 participants. Completed in 10 April 2020.

Timeline

7 June 2018

Primary endpoint
10 April 2020

10 April 2020

Quick facts

Lead sponsor	University Hospital of Ferrara
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	7 June 2018
Primary completion	10 April 2020
Estimated completion	10 April 2020
Sites	1 location across Italy

Drugs / interventions tested

Peristeen (Coloplast)

Conditions studied

Multiple Sclerosis — all drugs for Multiple Sclerosis →
Intestinal Dysfunction — all drugs for Intestinal Dysfunction →
Anal Incontinence — all drugs for Anal Incontinence →
Microbiota — all drugs for Microbiota →

Sponsor

University Hospital of Ferrara

Who can join

18 and older, any sex, with Multiple Sclerosis or Intestinal Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

MS (Multiple Sclerosis) is the most common neurological disease involving disabilities in young adults, with bowel symptoms, in particular constipation and fecal incontinence. The main objectives of the study are to assess the prevalence, characteristics, severity and impact on the Quality of Life of intestinal disorders in this population, to correlate the severity and characteristics of constipation and fecal incontinence with Intestinal Transit Time and the time dedicated to the evacuation, and how these items change in relation to the use of transanal irrigation (TAI). Another objective is to identify the composition of the intestinal microbiota in MS patients in relation to the type of bowel characteristics, comparing it with microbiota profile of the healthy population of the same region of origin, Emilia-Romagna, Italy.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Microbiota, IgA and Multiple Sclerosis.
Boussamet L, Rajoka MSR, Berthelot L. · · 2022 · cited 16× · PMID 35336190 · DOI 10.3390/microorganisms10030617
Trans-anal irrigation in patients with multiple sclerosis: Efficacy in treating disease-related bowel dysfunctions and impact on the gut microbiota: A monocentric prospective study.
Ascanelli S, Bombardini C, Chimisso L, Carcoforo P, et al · · 2022 · cited 4× · PMID 35832690 · DOI 10.1177/20552173221109771

Verify or expand the search:

Other recruiting trials for Multiple Sclerosis

Currently open trials in the same condition.

NCT07507084 — The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Wal · NA · recruiting
NCT07524231 — Evaluation of the Effects of Laughter Yoga · NA · recruiting
NCT07489794 — URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS · recruiting
NCT07236684 — Identification of Factors Related to UI in Patients With MS and EMG Assessment of PFM Activity · recruiting
NCT07500727 — Skeletal Muscle Aging and Responsiveness in Aged People With MS · NA · recruiting

Other University Hospital of Ferrara trials

Trials by the same sponsor.

NCT07244562 — Effects of Physical Exercise and Cognitive Training on Quality of Life in Older Women · NA · not yet recruiting
NCT07244536 — Effects of Physical Exercise and Cognitive Training on Quality of Life in Elderly Adults · NA · recruiting
NCT07118761 — Home-based Empowerment Through Physical Exercise Assisted by Technology for Frail Patients · NA · not yet recruiting
NCT06679517 — Observational Study Relating to the Long-term Follow-up of Patients with Severe Aortic Stenosis Evaluated for Percutaneo · enrolling by invitation
NCT07058896 — Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Severe Gait Impair · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04599595 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital of Ferrara
Last refreshed: 22 October 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04599595.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing