NCT04599244

Effect of Emergency Pulpotomy Versus Pulp Extirpation on Anesthetic Efficacy in Endodontic Treatment of Acute Pulpitis

Status unknown NA Last updated 22 October 2020

What this trial tests

NA trial testing emergency pulpotomy in Symptomatic Irreversible Pulpits in 78 participants. Status unknown.

Timeline

1 December 2020

Primary endpoint
1 December 2021

1 December 2022

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	78
Start date	1 December 2020
Primary completion	1 December 2021
Estimated completion	1 December 2022

Drugs / interventions tested

• emergency pulpotomy

Conditions studied

• Symptomatic Irreversible Pulpits — all drugs for Symptomatic Irreversible Pulpits →

Sponsor

Cairo University

Who can join

Adults 18 to 65, any sex, with Symptomatic Irreversible Pulpits. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, and one of the main reasons for seeking emergency dental treatment. Pain associated with irreversible pulpitis represents more than 45% of emergency patients in dental clinics. A pulpotomy has been demonstrated as an emergency intervention for effective pain relief by removing the coronal pulp tissue without penetrating radicular pulpal tissue. Inflammation and degeneration of the pulp usually progress apically from the point of infection, so selective removal of this tissue in the form of pulpotomy is usually effective in controlling pain and patient sedation.

The rationale behind emergency pulpotomy is relieving acute dental pain caused by irreversible pulpitis. However, there is still insufficient evidence to determine whether the presence, nature and duration of clinical symptoms gives accurate information about the extent of pulp inflammation, as pulpotomy was found to be an effective emergency treatment strategy with respect to relieving clinical symptoms, even in cases of irreversible pulpitis with symptomatic apical periodontitis . Advanced diagnostic strategies are needed to determine whether there is a correlation between clinical symptoms, actual pulpal inflammation and achieving adequate pain relief during and after treatment. Thus, we are conducting this study to assess the effect of emergency pulpotomy versus complete pulp extirpation on relieving acute dental pain of symptomatic irreversible pulpitis in mandibular molars. The expected benefit for the patients is to decrease pain during and after treatment. we also are trying to provide an evidence for the clinician in order to provide the best endodontic treatment without pain.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Vital Pulp Therapy in Teeth with Symptomatic Irreversible Pulpitis: A Systematic Review.
   Bafail AS. · · 2024 · cited 1× · PMID 39207274 · DOI 10.3290/j.ohpd.b5718325