Last reviewed · How we verify
NCT04598048: EMMACE-XL
Quality of Life Post-ACS in Participants from EMMACE
trial testing Questionnaire in Cardiovascular Diseases in 13,400 participants. Completed in 8 November 2024.
31 March 2021
Quick facts
| Lead sponsor | University of Leeds |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 13,400 |
| Start date | 27 September 2020 |
| Primary completion | 31 March 2021 |
| Estimated completion | 8 November 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Questionnaire
Conditions studied
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
University of Leeds
Who can join
Eligibility, any sex, with Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
EMMACE-XL will recruit participants who are survivors of acute coronary syndrome (a type of heart attack) to assess their health-related quality of life five years or more after their heart attack. We will invite surviving participants from the EMMACE 3 and 4 studies to consent to participate in EMMACE-XL study, they will be asked to complete one questionnaire relating to their health, medication and lifestyle. The questionnaire will be linked to their data collected as part of the EMMACE 3 and 4 studies including long term follow up data from NHS Digital. The data collected from all the studies will then be analysed to see if patient groups can be identified who are at risk of poorer quality of life and worse health outcomes. These groups can then be targeted with the aim of improving their health outcomes. The study will use statistical methods to look at the relationship of factors such as; medication adherence, comorbidities and patient demographics on health-related quality of life and health outcomes.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Sex differences in health-related quality of life trajectories following myocardial infarction: national longitudinal cohort study.
Dondo TB, Munyombwe T, Hall M, Hurdus B, et al · · 2022 · cited 6× · PMID 36351712 · DOI 10.1136/bmjopen-2022-062508
Verify or expand the search:
- PubMed search for NCT04598048
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04598048 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Leeds
- Last refreshed: 30 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04598048.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing