Last reviewed · How we verify
NCT04597489: FLORIDA
Fractional FLOw Reserve In Cardiovascular DiseAses
trial testing Fractional flow reserve in Coronary Artery Disease in 64,045 participants. Completed in 2 March 2020.
20 January 2020
Quick facts
| Lead sponsor | LinkCare GmbH |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 64,045 |
| Start date | 1 December 2019 |
| Primary completion | 20 January 2020 |
| Estimated completion | 2 March 2020 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Fractional flow reserve
- Angiography-only
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
Sponsor
LinkCare GmbH — full company profile →
Who can join
Eligibility, any sex, with Coronary Artery Disease or Acute Coronary Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The FLORIDA (Fractional FLOw Reserve In cardiovascular DiseAses) study sought to investigate outcomes of FFR-guided versus angiography-guided treatment strategies in a large, real-world cohort.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Fractional flow reserve measurements and long-term mortality-results from the FLORIDA study.
Boeckling F, Stähli BE, Rudolph T, Lutz M, et al · · 2024 · cited 1× · PMID 38404721 · DOI 10.3389/fcvm.2024.1337941
Verify or expand the search:
- PubMed search for NCT04597489
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Fractional flow reserve
Trials testing the same drug.
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- NCT02015832 — Trial Evaluating New Strategy in the Functional Assessment of 3-vessel Disease Using SYNTAXII Score in Patients With PCI · completed
- NCT02073422 — FAMOUS-NSTEMI MRI Sub-Study · completed
Other recruiting trials for Coronary Artery Disease
Currently open trials in the same condition.
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- NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting
Other LinkCare GmbH trials
Trials by the same sponsor.
- NCT04184596 — Preferences in Pain Treatment: A Discrete Choice Experiment in Patients With Peripheral Neuropathic Pain (pNP) · completed
- NCT03778450 — Long-term Opioid Therapy, Misuse and Mortality in Patients With Chronic Non-cancer Pain in Germany · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04597489 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by LinkCare GmbH
- Last refreshed: 22 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04597489.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing