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NCT04596787
Bilateral Thoracic Paravertebral Blocks in Obese and Non-obese Patients Undergoing Reduction Mammaplasty
trial testing Bilateral Thoracic paravertebral block in Pain, Postoperative in 82 participants. Completed in 28 February 2020.
28 February 2020
Quick facts
| Lead sponsor | Istanbul University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 82 |
| Start date | 1 December 2016 |
| Primary completion | 28 February 2020 |
| Estimated completion | 28 February 2020 |
Drugs / interventions tested
- Bilateral Thoracic paravertebral block
Conditions studied
- Pain, Postoperative — all drugs for Pain, Postoperative →
- Obesity — all drugs for Obesity →
- Thoracic Paravertebral Blocks — all drugs for Thoracic Paravertebral Blocks →
- Ultrasound — all drugs for Ultrasound →
Sponsor
Istanbul University
Who can join
Adults 18 to 65, female only, with Pain, Postoperative or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aim: Although regional anesthesia (RA) techniques are advantageous in the anesthetic management of obese patients (body mass index (BMI)≥30); their performances can still be associated with technical difficulties and greater failure rates. The aim of this study is to compare the performance properties and analgesic efficacy of ultrasound (US)-guided bilateral thoracic paravertebral blocks (TPVBs) in obese and non-obese patients. Material methods: After obtaining ethics committee approval; data of 82 patients, who underwent elective bilateral reduction mammaplasty under general anesthesia with adjunctive TPVB analgesia between December of 2016 and February of 2020, were reviewed. Patients were allocated into two groups with respect to their BMI scores (Group NO: BMI\<30 and Group O: BMI≥30). Demographics, TPVB ideal US image visualization and performance times, needle tip visualisation and TPVB performance difficulties, number of needle maneuvers, surgical, anesthetic and analgesic follow-up parameters, incidence of postoperative nausea vomiting (PONV), sleep duration, length of postanesthesia care unit (PACU) and hospital stay, patient and surgeon satisfaction scores were all investigated and compared.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of Performance Characteristics and Efficacy of Bilateral Thoracic Paravertebral Blocks in Obese and Non-Obese Patients Undergoing Reduction Mammaplasty Surgery: A Historical Cohort Study.
Şalvız EA, Bingül ES, Güzel M, Savran Karadeniz M, et al · · 2023 · cited 5× · PMID 36763114 · DOI 10.1007/s00266-023-03270-w
Verify or expand the search:
- PubMed search for NCT04596787
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04596787 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul University
- Last refreshed: 22 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04596787.
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