Last reviewed · How we verify
NCT04589923
The VISION-Acute Study
trial testing Lifelight® Data Collect Blood Pressure Group in Hypertension in 127 participants. Completed in 7 May 2022.
29 April 2021
Quick facts
| Lead sponsor | Xim Limited |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 127 |
| Start date | 14 September 2020 |
| Primary completion | 29 April 2021 |
| Estimated completion | 7 May 2022 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Lifelight® Data Collect Blood Pressure Group
- Lifelight® Data Collect Oxygen Saturation Group
Conditions studied
- Hypertension — all drugs for Hypertension →
- Hypoxia — all drugs for Hypoxia →
- Hypotension — all drugs for Hypotension →
Sponsor
Xim Limited
Who can join
18 and older, any sex, with Hypertension or Hypoxia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
AIM: We propose an innovative approach using Lifelight® smart technology that will enable the continued provision of high level patient care at the same time as reducing pressure on nursing and equipment resources. METHOD : Lifelight® is a computer program ("app") which can be used on smart devices that contain a camera. It is able to measure all of the vital signs by measuring very small changes in skin colour that occur each time the heart beats. This means that it does not need to touch the patient. We believe this could be an effective way of measuring vital signs, especially during the COVID-19 pandemic when prevention of cross-contamination between patients is essential. Patients are also likely to be reassured by a contactless approach. During this study, we will recruit two groups of people who are hospitalised with an acute illness. The first group will be people expected to have abnormal blood oxygen levels such as those with acute respiratory problems including those with COVID-19. The second group will be people expected to have abnormal blood pressure. These Lifelight vital signs will be compared to measurements from standard clinical equipment. The exact number of participants recruited will depend on how quickly the app "learns" and how many of the vital signs collected are outside of the normal range. For the first group of participants, we will use a camera to collect data about the changes in their face and use this to teach the app how to measure blood oxygen level and also to check how well the app measures blood oxygen level, heart rate and respiratory rate. For the second group of participants, we will use a camera to collect data about the changes in their face to check how well the app measures blood pressure and respiratory rate. All of the data will be kept secure and participants will not be able to be identified.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Hypertension and COVID-19: Updates from the era of vaccines and variants.
Swamy S, Koch CA, Hannah-Shmouni F, Schiffrin EL, et al · · 2022 · cited 10× · PMID 34900602 · DOI 10.1016/j.jcte.2021.100285 -
Measurement of Vital Signs Using Lifelight Remote Photoplethysmography: Results of the VISION-D and VISION-V Observational Studies.
Heiden E, Jones T, Brogaard Maczka A, Kapoor M, et al · · 2022 · cited 9× · PMID 36374541 · DOI 10.2196/36340
Verify or expand the search:
- PubMed search for NCT04589923
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Xim Limited trials
Trials by the same sponsor.
- NCT06325384 — Real World Evaluation of Lifelight®: A Contactless Vital Signs Monitor for Self-monitoring Blood Pressure and Its Compar · NA · recruiting
- NCT06535152 — Lifelight Non-Invasive Blood Pressure and Heart Rate Validation Study · NA · completed
- NCT05850013 — The Measurement of Vital Signs in Children by Lifelight® Software in Comparison to the Standard of Care · completed
- NCT04763746 — The Measurement of VItal SIgns by Lifelight® Software in comparisON to the Standard of Care - Multi-site Development · completed
- NCT03998098 — A Single Center Study to Demonstrate the Safety and Performance of Lifelight® First Software Application · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04589923 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xim Limited
- Last refreshed: 20 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04589923.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing