Last reviewed · How we verify
NCT04584580
D-dimer Adjusted Versus Therapeutic Dose Low-molecular-weight Heparin in Patients With COVID-19 Pneumonia
Phase 4 trial testing low-molecular-weight heparin in Coronavirus Disease (COVID)19 in 50 participants. Status unknown.
31 October 2020
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 50 |
| Start date | 1 August 2020 |
| Primary completion | 31 October 2020 |
| Estimated completion | 31 December 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- low-molecular-weight heparin
Conditions studied
- Coronavirus Disease (COVID)19 — all drugs for Coronavirus Disease (COVID)19 →
Sponsor
Ain Shams University
Who can join
18 and older, any sex, with Coronavirus Disease (COVID)19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
evaluation of the efficacy and safety of D-dimer adjusted heparin versus therapeutic dose heparin in patients with COVID-19 Pneumonia.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19.
Bernard I, Limonta D, Mahal LK, Hobman TC. · · 2020 · cited 128× · PMID 33375371 · DOI 10.3390/v13010029 -
Anticoagulants for people hospitalised with COVID-19: a rapid review
Flumignan RL, Civile VT, Tinôco JDS, Pascoal PI, et al · · 2022 · cited 41× · PMID 35244208 · DOI 10.1002/14651858.cd013739.pub2 -
Endothelial Dysfunction and SARS-CoV-2 Infection: Association and Therapeutic Strategies.
Deng H, Tang TX, Chen D, Tang LS, et al · · 2021 · cited 17× · PMID 34064553 · DOI 10.3390/pathogens10050582 -
Role of Therapeutic Anticoagulation in COVID-19: The Current Situation.
Rahi MS, Parekh J, Pednekar P, Mudgal M, et al · · 2023 · cited 4× · PMID 37367086 · DOI 10.3390/hematolrep15020037
Verify or expand the search:
- PubMed search for NCT04584580
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04584580 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 14 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04584580.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing