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NCT04584424
Prognostic Factors and Outcomes of COVID-19 Cases in Ethiopia
trial testing The study does not required in Epidemiology in 6,390 participants. Completed in 14 November 2022.
14 November 2022
Quick facts
| Lead sponsor | Ethiopian Public Health Institute |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 6,390 |
| Start date | 30 October 2020 |
| Primary completion | 14 November 2022 |
| Estimated completion | 14 November 2022 |
| Sites | 1 location across Ethiopia |
Drugs / interventions tested
- The study does not required
Conditions studied
- Epidemiology — all drugs for Epidemiology →
- Clinical — all drugs for Clinical →
- Nutritional-status — all drugs for Nutritional-status →
- Immunologic Defect — all drugs for Immunologic Defect →
Sponsor
Ethiopian Public Health Institute
Who can join
Eligibility, any sex, with Epidemiology or Clinical. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study will be to determine the epidemiological and clinical features of COVID-19 cases, immunological and virological courses, interaction with nutritional status, and response to treatment for COVID-19 patients admitted to treatment centers in Ethiopia. Methods: This multi-site cohort enrolls, patients with confirmed COVID-19 infection admitted to treatment centers will be enrolled irrespective of their symptoms and followed up for 12 months. Baseline epidemiological, clinical, laboratory and imaging data will be collected from treatment records, interviews, physical measurements and biological samples. Endline data involves treatment and prognostic outcomes to be measured using different biomarkers and clinical parameters, The patients will be followed up in the selected treatment centers for COVID-19 infection. For all data collected both descriptive and multivariable analyses will be performed to isolated determinants of the treatment outcome and prognosis to generate relevant information for informed prevention and case management.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Prognostic factors and outcomes of COVID-19 cases in Ethiopia: multi-center cohort study protocol.
Abdella S, Tessema M, Tasew G, Defar A, et al · · 2021 · cited 4× · PMID 34530744 · DOI 10.1186/s12879-021-06652-0 -
Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19.
Wolday D, Gebrehiwot AG, Le Minh AN, Rameto MA, et al · · 2025 · cited 1× · PMID 40475767 · DOI 10.3389/fimmu.2025.1575135 -
Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19
Wolday D, Gebrehiwot AG, Rameto MA, Abdella S, et al · · 2024 · DOI 10.1101/2024.10.09.24315196
Verify or expand the search:
- PubMed search for NCT04584424
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ethiopian Public Health Institute trials
Trials by the same sponsor.
- NCT05682261 — The Effect of Multiple Micronutrient Supplements in Reducing Anemia in Women of Reproductive Age · NA · completed
- NCT05669209 — Causes of Anemia Among Women of Reproductive Age · completed
- NCT03394963 — Developing and Validating Food-based Dietary Guidelines and a Healthy Eating Index · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04584424 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ethiopian Public Health Institute
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04584424.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing