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NCT04584424

Prognostic Factors and Outcomes of COVID-19 Cases in Ethiopia

Completed Last updated 19 September 2024
What this trial tests

trial testing The study does not required in Epidemiology in 6,390 participants. Completed in 14 November 2022.

Timeline
30 October 2020
Primary endpoint
14 November 2022
14 November 2022

Quick facts

Lead sponsorEthiopian Public Health Institute
StatusCompleted
Study typeOBSERVATIONAL
Enrollment6,390
Start date30 October 2020
Primary completion14 November 2022
Estimated completion14 November 2022
Sites1 location across Ethiopia

Drugs / interventions tested

Conditions studied

Sponsor

Ethiopian Public Health Institute

Who can join

Eligibility, any sex, with Epidemiology or Clinical. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study will be to determine the epidemiological and clinical features of COVID-19 cases, immunological and virological courses, interaction with nutritional status, and response to treatment for COVID-19 patients admitted to treatment centers in Ethiopia. Methods: This multi-site cohort enrolls, patients with confirmed COVID-19 infection admitted to treatment centers will be enrolled irrespective of their symptoms and followed up for 12 months. Baseline epidemiological, clinical, laboratory and imaging data will be collected from treatment records, interviews, physical measurements and biological samples. Endline data involves treatment and prognostic outcomes to be measured using different biomarkers and clinical parameters, The patients will be followed up in the selected treatment centers for COVID-19 infection. For all data collected both descriptive and multivariable analyses will be performed to isolated determinants of the treatment outcome and prognosis to generate relevant information for informed prevention and case management.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Prognostic factors and outcomes of COVID-19 cases in Ethiopia: multi-center cohort study protocol.
    Abdella S, Tessema M, Tasew G, Defar A, et al · · 2021 · cited 4× · PMID 34530744 · DOI 10.1186/s12879-021-06652-0
  2. Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19.
    Wolday D, Gebrehiwot AG, Le Minh AN, Rameto MA, et al · · 2025 · cited 1× · PMID 40475767 · DOI 10.3389/fimmu.2025.1575135
  3. Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19
    Wolday D, Gebrehiwot AG, Rameto MA, Abdella S, et al · · 2024 · DOI 10.1101/2024.10.09.24315196

Verify or expand the search:

Other recruiting trials for Epidemiology

Currently open trials in the same condition.

Other Ethiopian Public Health Institute trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04584424.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing