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NCT04583631

Relationship of Endoplasmic Reticulum Stress and Adenoid Diseases

Completed Last updated 27 September 2021
What this trial tests

trial testing Adenoidectomy surgery in Adenoiditis Acute Infective in 54 participants. Completed in 1 August 2019.

Timeline
1 November 2018
Primary endpoint
1 August 2019
1 August 2019

Quick facts

Lead sponsorSelcuk University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment54
Start date1 November 2018
Primary completion1 August 2019
Estimated completion1 August 2019
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Selcuk University

Who can join

Adults 3 to 9, any sex, with Adenoiditis Acute Infective. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Adenoid tissue is a significant organ for the performing of immune systems in children. The Endoplasmic Reticulum (ER), is an organelle needed for the care of a stable function of cells. The purpose of the study was to explore the correlation among ER stress and adenoid tissue disorders and to explain the structure of diseases related to the immune system.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Possible role of endoplasmic reticulum stress in the pathogenesis of chronic adenoiditis and adenoid hypertrophy: A prospective, parallel-group study.
    Onal M, Elsurer C, Duran T, Kocak N, et al · · 2024 · cited 2× · PMID 38596230 · DOI 10.1002/lio2.1240
  2. Endoplasmic reticulum stress in disease pathogenesis: its implications for therapy.
    Wei S, Zhang N, Zhang H, Chen Z, et al · · 2026 · PMID 41986307 · DOI 10.1038/s41392-026-02600-z
  3. Possible role of endoplasmic reticulum stress in pathogenesis of chronic adenoiditis and adenoid hypertrophy: a prospective, parallel-group study
    Onal O, Onal M, Elsurer C, Duran T, et al · · 2023 · DOI 10.22541/au.168180137.72504092/v1

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