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NCT04583098
The Effect of Fecal Microbiota Transplantation on the Decolonization of Multidrug-resistant Organisms
trial testing fecal microbiota transplantation in Carbapenem-Resistant Enterobacteriaceae Infection in 100 participants. Completed in 31 August 2024.
31 August 2023
Quick facts
| Lead sponsor | Chuncheon Sacred Heart Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 14 March 2019 |
| Primary completion | 31 August 2023 |
| Estimated completion | 31 August 2024 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- fecal microbiota transplantation — full drug profile →
Conditions studied
- Carbapenem-Resistant Enterobacteriaceae Infection — all drugs for Carbapenem-Resistant Enterobacteriaceae Infection →
- Vancomycin-Resistant Enterococcal Infection — all drugs for Vancomycin-Resistant Enterococcal Infection →
Sponsor
Chuncheon Sacred Heart Hospital
Who can join
19 and older, any sex, with Carbapenem-Resistant Enterobacteriaceae Infection or Vancomycin-Resistant Enterococcal Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to assess the effect of fecal microbiota transplantation for the decolonization of carbapenem-resistant Enterobacteriaceae or vancomycin-resistant Enterococci in the gut.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Gut Microbiota Modulation and Prevention of Dysbiosis as an Alternative Approach to Antimicrobial Resistance: A Narrative Review.
Matzaras R, Nikopoulou A, Protonotariou E, Christaki E. · · 2022 · cited 34× · PMID 36568836 -
Alteration of Gut Microbiota in Carbapenem-Resistant Enterobacteriaceae Carriers during Fecal Microbiota Transplantation According to Decolonization Periods.
Lee JJ, Yong D, Suk KT, Kim DJ, et al · · 2021 · cited 19× · PMID 33578974 · DOI 10.3390/microorganisms9020352 -
Is there a role of faecal microbiota transplantation in reducing antibiotic resistance burden in gut? A systematic review and Meta-analysis.
Dharmaratne P, Rahman N, Leung A, Ip M. · · 2021 · cited 17× · PMID 34170204 · DOI 10.1080/07853890.2021.1927170 -
Antimicrobial Resistance: The Answers.
Millar BC, Cates MJ, Torrisi MS, Round AJ, et al · · 2026 · PMID 41727556 · DOI 10.3389/bjbs.2026.15559 -
286. The Effect of Fecal Microbiota Transplantation on Decolonization of Multidrug-resistant Organisms in the gut
· 2023
Verify or expand the search:
- PubMed search for NCT04583098
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of fecal microbiota transplantation
Trials testing the same drug.
- NCT06475430 — Fecal Microbiota Transplantation in the Treatment of Major LARS · NA · not yet recruiting
- NCT06496412 — Safety and Efficacy of Fecal Microbiota Transplantation on Cognitive Function in T1DM · NA · recruiting
- NCT06673134 — Prospective Cohort Establishment and Clinical Observation of Children With Crohn's Disease · active not recruiting
- NCT06001333 — Efficacy and Safety of FMT for the Decolonization of MDROs in the Intestinal Tract · NA · recruiting
- NCT05170971 — Fecal Microbiota Transplantation for Liver Failure · NA · recruiting
Other recruiting trials for Carbapenem-Resistant Enterobacteriaceae Infection
Currently open trials in the same condition.
- NCT05979545 — EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics · Phase 4 · recruiting
- NCT06051513 — Efficacy and Safety of Colistimethate Sodium for Injection in The Treatment of Carbapenem-Resistant Enterobacteriaceae I · NA · recruiting
- NCT07086391 — Different Methods of Aerosolized Polymyxin B Inhalation for Treating Carbapenem-Resistant Gram-Negative Bacterial Pneumo · recruiting
- NCT05871476 — Interventions to Decrease CRE Colonization and Transmission Between Hospitals, Households, Communities and Domesticated · NA · recruiting
- NCT04535661 — Risk Factors for Colonization or Infection With Carbapenem-Resistant Enterobacteriaceae in Children · recruiting
Other Chuncheon Sacred Heart Hospital trials
Trials by the same sponsor.
- NCT07039955 — Effect of Daily Chlorhexidine Bathing and Antibiotic/PPI Stewardship on Prevention of CPE Transmission and Infection · NA · enrolling by invitation
- NCT07001228 — Scapular Dyskinesis With Impingement Syndrome · NA · not yet recruiting
- NCT06878391 — ISB With SSNB & ANB · NA · recruiting
- NCT06055491 — Vitamin D3 Combined With Strengthening Exercise for Lateral Epicondylitis of Elbow · NA · unknown
- NCT06055478 — Effect of Suprascapular Nerve Block and Axillary Nerve Block After Arthroscopic Rotator Cuff Repair · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04583098 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chuncheon Sacred Heart Hospital
- Last refreshed: 19 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04583098.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing