Last reviewed · How we verify
NCT04582578
Resynchronization for Ambulatory Heart Failure Trial in Patients With Preserved LV Function
NA trial testing CRT in Heart Failure. Withdrawn.
23 February 2023
Quick facts
| Lead sponsor | Anthony Tang |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Start date | 3 November 2021 |
| Primary completion | 23 February 2023 |
| Estimated completion | 23 February 2023 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- CRT
Conditions studied
- Heart Failure — all drugs for Heart Failure →
Sponsor
Anthony Tang
Who can join
18 and older, any sex, with Heart Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial will compare two management strategies for HF patients with preserved LV function in sinus rhythm and LBBB. The control group will be treated with practice guideline optimal medical therapy for HF. The experimental group will be treated with CRT in addition to optimal medical therapy for HF. In addition, the trial will further compare two methods of delivering CRT. One experimental group will receive BiV-CRT, while the second experimental group will receive CS-CRT.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Conduction system pacing on track to replace CRT? Review of current evidence and prospects of conduction system pacing.
Moustafa AT, Tang AS, Khan HR. · · 2023 · cited 4× · PMID 37649666 · DOI 10.3389/fcvm.2023.1220709
Verify or expand the search:
- PubMed search for NCT04582578
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of CRT
Trials testing the same drug.
- NCT05912036 — The CORTEX Randomized Control Trial · NA · unknown
- NCT05732285 — A Pilot Randomized Controlled Trial: CoINTEGRATE · NA · completed
- NCT05854290 — Comprehensive Cognitive and Affective Intervention for Mild Cognitive Impairment (MCI) for Foreign-Born Arab Americans · NA · terminated
- NCT04564482 — PD-L1 PET Imaging During Neoadjuvant (Chemo)Radiotherapy in Esophageal and Rectal Cancer · NA · recruiting
- NCT05669092 — A Phase III Trial of Anus-preservation in Low Rectal Adenocarcinoma Based on MMR/MSI Status · Phase 3 · unknown
Other recruiting trials for Heart Failure
Currently open trials in the same condition.
- NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
- NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
- NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
- NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
- NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting
Other Anthony Tang trials
Trials by the same sponsor.
- NCT05923658 — How Clinicians Manage Their Patients Who May Need Antithrombotic Care · unknown
- NCT05118893 — Randomized Ablation-based AF Rhythm-control Versus Rate-control in Patients With HF and High-burden AF Extend · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04582578 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Anthony Tang
- Last refreshed: 9 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04582578.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing