NCT04582305 is a Phase 4 clinical trial of Bleomycin in Keloid, sponsored by Erasmus Medical Center.

Who is sponsoring NCT04582305?

NCT04582305 is sponsored by Erasmus Medical Center.

What drugs are being tested in NCT04582305?

Interventions in NCT04582305: Bleomycin, Normal saline.

Is NCT04582305 still recruiting?

NCT04582305 is currently status unknown. Last updated 9 November 2022.

Last reviewed 2022-11-09 · How we verify

NCT04582305

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Bleomycin Jet Injections in Keloids

Status unknown Phase 4 Last updated 9 November 2022

What this trial tests

Phase 4 trial testing Bleomycin in Keloid in 14 participants. Status unknown.

Timeline

18 March 2022

Primary endpoint
18 November 2022

30 March 2023

Quick facts

Lead sponsor	Erasmus Medical Center
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	14
Start date	18 March 2022
Primary completion	18 November 2022
Estimated completion	30 March 2023
Sites	1 location across Netherlands

Drugs / interventions tested

Bleomycin (BLEOMYCIN) — full drug profile →
Normal saline

Conditions studied

Keloid — all drugs for Keloid →

Sponsor

Erasmus Medical Center

Who can join

18 and older, any sex, with Keloid. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a single center, double-blind (patient and investigator), randomized, placebo-controlled study with a split-lesion design, in which selected keloids will receive three consecutive treatments of a) bleomycin and b) placebo (saline (NaCl 0,9%)), administered with an electronic pneumatic jet injector.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Current State of Clinical Trials for Keloid Management: An Analysis of Trials Registered on ClinicalTrials.gov.
Park S, Li D, Guo L, Xu X. · · 2026 · PMID 42077711 · DOI 10.7759/cureus.106243

Verify or expand the search:

Other trials of Bleomycin

Trials testing the same drug.

NCT07041749 — Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar Wart · NA · not yet recruiting
NCT07320001 — Injection Sclerotherapy With Bleomycin VS Doxycycline in Patients With Lymphatic Malformations · Phase 2 · not yet recruiting
NCT06647342 — The Effect of Reduced Bleomycin in Electrochemotherapy Treatment · Phase 4 · recruiting
NCT06189092 — Treatment of Low-flow Venous Malformations With Electrosclerotherapy. Prospective Observational Study · recruiting
NCT06437158 — Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients · Phase 2 · recruiting

Other recruiting trials for Keloid

Currently open trials in the same condition.

NCT06431360 — Effect of Strontium-90 Brachytherapy Combined With Hyperthermia in the Treatment of Keloid · NA · recruiting
NCT06138964 — Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars · Phase 2 · recruiting

Other Erasmus Medical Center trials

Trials by the same sponsor.

NCT07406269 — Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery · NA · not yet recruiting
NCT07402109 — CBCT Guided Markerless SBRT for Renal Cell Cancer · NA · recruiting
NCT07383194 — Prediction Models for LDLT Outcomes · not yet recruiting
NCT07426575 — Evaluating the Usability of New Dialysis Bags · not yet recruiting
NCT07329296 — The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04582305 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Erasmus Medical Center
Last refreshed: 9 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04582305.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing