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NCT04581590
The Impact TDCS-linked Motor and Cognitive Training Gains in Parkinson's Disease
NA trial testing Cognitive training in Parkinson Disease in 242 participants. Participants enrolled and being followed up; not accepting new ones.
15 July 2024
Quick facts
| Lead sponsor | Federal University of Paraíba |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 242 |
| Start date | 3 October 2022 |
| Primary completion | 15 July 2024 |
| Estimated completion | 2 February 2026 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Cognitive training
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
- Cognition Disorder — all drugs for Cognition Disorder →
- Motor Disorders — all drugs for Motor Disorders →
Sponsor
Federal University of Paraíba
Who can join
Adults 40 to 70, any sex, with Parkinson Disease or Cognition Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a group controlled clinical trial. Parallel study, patients aged 40-70 years, with Parkinson disease. Twelve sessions, three times a week, for 30 minutes, simultaneously to the rehabilitation program. Training will consist of Transcranial Direct Current Stimulation linked dual-task exercises or dual-taks exercises with cognitive training, applied three times a week during four weeks. The investigators will used instruments: dual-task gait speed (Auditory Stroop Task ), executive function (Wisconsin Card Sorting Test , Auditory Stroop Test, Trail Making Test, Verbal Fluency Test and Montreal Cognitive Assessment), and, the objective is to examine task-dependency in enhancing the effects of tDCS-linked rehabilitation training on PD and the relationships between baseline outcomes in responders and non-responders to therapy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Can Task Specificity Impact tDCS-Linked to Dual Task Training Gains in Parkinson's Disease? A Protocol for a Randomized Controlled Trial.
Costa-Ribeiro A, Andrade SMMDS, Férrer MLV, Silva OAPD, et al · · 2021 · cited 3× · PMID 34276344 · DOI 10.3389/fnagi.2021.684689
Verify or expand the search:
- PubMed search for NCT04581590
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
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- NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
- NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting
Other Federal University of Paraíba trials
Trials by the same sponsor.
- NCT07192003 — Immediate Effects of Flossband and Mobilization With Movement on Shoulder Mobility in Volleyball Athletes · NA · not yet recruiting
- NCT06827379 — Acute Effects of Inspiratory Muscle Training on Peripheral Muscle Metabolism and Autonomic Response in COPD Patients · NA · enrolling by invitation
- NCT06542666 — Cognitive Functional Therapy for Chronic Shoulder Pain: Pilot and Feasibility Study · NA · recruiting
- NCT06661681 — Cognitive Functional Therapy for Treating Individuals With Chronic Shoulder Pain · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04581590 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federal University of Paraíba
- Last refreshed: 17 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04581590.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing